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Home > Products >  AGOMELATINE 138112-76-2

AGOMELATINE 138112-76-2 CAS NO.138112-76-2

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Keywords

  • 138112-76-2
  • AGOMELATINE

Quick Details

  • ProName: AGOMELATINE 138112-76-2
  • CasNo: 138112-76-2
  • Molecular Formula: C15H17NO2
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99%
  • LimitNum: 0 Metric Ton

Superiority

AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-

Details


AGOMELATINE Chemical Properties

mp  107-109°C
storage temp.  -20°C Freezer
CAS DataBase Reference 138112-76-2(CAS DataBase Reference)



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MSDS Information 



AGOMELATINE Usage And Synthesis

Chemical Properties White Solid
Usage Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of
Usage Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.

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