Clindamycin phosphate 24729-96-2 NoI in the market CAS NO.24729-96-2

Synonyms: (2s-trans)-;2-(dihydrogenphosphate;7(s)-chloro-7-deoxylincomycin2-phosphate;cleocinphosphate;dalacinp;l-threo-alpha-d-galacto-octapyranoside,methyl7-chloro-6,7,8-trideoxy-6-(((1-m;u28508;methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-alpha-d-galacto-octopyranoside 2-(dihydrogen phosphate)
CAS: 24729-96-2
MF: C18H34ClN2O8PS
MW: 504.97
EINECS: 246-433-0
Product Categories: Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);API's;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 24729-96-2.mol
Clindamycin phosphate Structure
Clindamycin phosphate Chemical Properties
Melting point  114 °C
refractive index  122 ° (C=1, H2O)
storage temp.  2-8°C
solubility  DMSO: soluble224mg/mL at 25°C
Water Solubility  Freely soluble in water
Merck  2356
Stability: Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins.
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  36-26
WGK Germany  3
RTECS  GF2625000
HS Code  29419000

Clindamycin phosphate Usage And Synthesis
Chemical Properties solid
Uses antibacterial
Uses Clindamycin (C580000) impurity in bulk drug.
Uses A highly water soluble Clindamycin prodrug.
Uses Clindamycin 2-phosphate is a a salt of clincamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.
Uses Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.
Clindamycin phosphate Preparation Products And Raw materials
Raw materials Clindamycin