Dehydroepiandrosterone acetate CAS NO.853-23-6

Dehydroepiandrosterone acetate Basic information
Product Name:    Dehydroepiandrosterone acetate
Synonyms:    3B-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE ACETATE;3B-HYDROXYANDROST-5-EN-17-ONEACETATE;3-(ACETYLOXY)ANDROST-5-ENE-17-ONE;5-ANDROSTEN-3-BETA-ACETOXY-3-ONE;5-ANDROSTEN-3BETA-OL-17-ONE 3-ACETATE;5-ANDROSTEN-3-BETA-OL-17-ONE ACETATE
CAS:    853-23-6
MF:    C21H30O3
MW:    330.47
EINECS:    212-714-1
Product Categories:    Intermediates & Fine Chemicals;17-Ketosteroids;Pharmaceutical Intermediates;Biochemistry;Hydroxyketosteroids;Chemistry;Steroids;Metabolites & Impurities;Pharmaceuticals;API;Inhibitors
Mol File:    853-23-6.mol

Dehydroepiandrosterone acetate Chemical Properties
Melting point     168-170 °C(lit.)
Boiling point     407.89°C (rough estimate)
density     1.0998 (rough estimate)
vapor pressure     0Pa at 20℃
refractive index     1.5192 (estimate)
storage temp.     Refrigerator
optical activity    [α]20/D +2.4°, c = 2 in ethanol
Water Solubility     11.5mg/L(temperature not stated)
InChIKey    NCMZQTLCXHGLOK-KJBVPOJVSA-N
LogP    5.1 at 20℃
CAS DataBase Reference    853-23-6

Dehydroepiandrosterone acetate Usage And Synthesis
Chemical Properties    Off-White Solid
Uses    Menopausal syndrome
Uses    A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function
Flammability and Explosibility    Notclassified
Biological Activity    Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.
in vivo    Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.