- Product Details
Keywords
- X-PHOS
- 1'-BIPHENYL;2-DICYCLOHEXYLPHOSPHINO-2'
- 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE
Quick Details
- ProName: X-PHOS
- CasNo: 564483-18-7
- Molecular Formula: C33H49P
- Appearance: Powder
- Application: Used to protect alcohols during organi...
- DeliveryTime: instock
- PackAge: according to the need of packing
- Port: ShangHai
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 98%
- Storage: Sealing/Low Temperature
- Transportation: air sea or courier
- LimitNum: 1 Gram
Superiority
Product Name: tert-Butyldimethylsilyl chloride
MF: C6H15ClSi
MW: 150.72
EINECS: 242-042-4
Melting point 86-89 °C (lit.)
Boiling point 125 °C (lit.)
density 0.87 g/mL at 20 °C(lit.)
refractive index n20/D 1.46
Fp 73 °F
storage temp. Store at 5°C
form Liquid
color Clear colorless
Specific Gravity 1.225
Water Solubility Soluble in chloroform and ethyl acetate. Insoluble in water.
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN 505999
InChIKey BCNZYOJHNLTNEZ-UHFFFAOYSA-N
CAS DataBase Reference 18162-48-6(CAS DataBase Reference)
NIST Chemistry Reference Silane, chloro(1,1-dimethylethyl)dimethyl-(18162-48-6)
EPA Substance Registry System Silane, chloro(1,1-dimethylethyl)dimethyl- (18162-48-6)
Safety Information
Hazard Codes C,F,T,Xn
Risk Statements 22-35-40-34-10-19-11-67-65-63-48/20-20/21/22-45-23/24/25-37-36/37/38
Safety Statements 26-36/37/39-46-62-45-25-16-28-27-33-29-53-36/37
RIDADR UN 2925 4.1/PG 2
WGK Germany 2
RTECS VV2000000
F 10-21
Hazard Note Flammable/Corrosive/Moisture Sensitive
TSCA Yes
HazardClass 4.1
PackingGroup III
HS Code 29310095
MSDS Information
Provider Language
TBDMCS English
SigmaAldrich English
ACROS English
ALFA English
tert-Butyldimethylsilyl chloride Usage And Synthesis
Introduction Triethylchlorosilane is a clear, colourless to yellowish, pungent smelling, caustic and flammable liquid. It can be dissolved in non-protonating solvents without decomposition.
It may be used as silylating agent for dervatization of primary and secondary alcohols etc.. Also it may be used to protect allylic esters as silylketene acetal which is ore stable but less volatile derivates than trimethylchlorosilane.
Chemical Properties White solid
Uses Used to protect alcohols during organic synthesis.
Definition ChEBI: A silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a derivatisation agent used in gas chromatography/mass spectrometry ap lications.
Hazard Moderately toxic.
Purification Methods Fractionally distil it at atmospheric pressure. [Sommer & Tyler J Am Chem Soc 76 1030 1954, Corey & Venkateswarlu J Am Chem Soc 94 6190 1972, Beilstein 4 IV 4076.]
tert-Butyldimethylsilyl chloride Preparation Products And Raw materials
Raw materials Pentane-->tert-Butyllithium-->Dichlorodimethylsilane
Preparation Products 5-(AMINOMETHYL)-1-METHYLPYRROLIDIN-2-ONE-->(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one-->beta-Methyl vinyl phosphate (MAP)-->2-CYANOPYRIDINE-4-CARBOXALDEHYDE-->4-(HYDROXYMETHYL)PICOLINITRILE-->Simvastatin-->2-Chloro-4-nitrophenyl-alpha-L-fucopyranoside-->4-Mercaptophenylboronic acid-->Montelukast-->Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester-->Calcipotriene-->BIS(T-BUTYLDIMETHYLSILOXY)ETHANE
Details
Melting point 86-89 °C (lit.)
Boiling point 125 °C (lit.)
density 0.87 g/mL at 20 °C(lit.)
refractive index n20/D 1.46
Fp 73 °F
storage temp. Store at 5°C
form Liquid
color Clear colorless
Specific Gravity 1.225
Water Solubility Soluble in chloroform and ethyl acetate. Insoluble in water.
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN 505999
InChIKey BCNZYOJHNLTNEZ-UHFFFAOYSA-N
Hazard Note Flammable/Corrosive/Moisture Sensitive
TSCA Yes
HazardClass 4.1
PackingGroup III
HS Code 29310095SHANGHAI MINSTAR CHEMICAL CO., LTD. is a leading, experienced, professional supplier of API & intermediates, plant extract, food additive, fine chemicals and industry chemicals, etc. Our efforts are constantly dedicated to supplying customers with good quality products at competitive prices consistent with service that meets customers’ needs. In the past years, our products were exported to more than 50 countries and regions in Asia, Europe, Africa, Middle East and America and commanded a good reputation. MINSTAR selects high technology and market oriented products as her source of main business development strategy. Once we start, we do not just supply our own products. And in the years of development to meet customer demand for different kinds of products, we are helping to purchase other products too. Now we have completed our supplying chains for fine chemical & API industry, MINSTAR provides customers with optimal solution for related products & service demand -like related production information, product knowledge, optimum application method, since we own the R&D Laboratory Department, modern equipments, 2 production bases in Zhengjiang & Anhui provinces, fundamental and specific training including seminars.