Pyraclostrobin CAS NO.175013-18-0

Product Name:    Pyraclostrobin
Synonyms:    Pyrazole permethrin;METHYL [2-[1-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YLOXYMETHYL]PHENYL]METHOXYCARBAMATE;INSIGNIA;HEADLINE;BAS 500 F;CABRIO;OPERA;PYRACLOSTROBIN
CAS:    175013-18-0
MF:    C19H18ClN3O4
MW:    387.82
EINECS:    605-747-1
Product Categories:    Agro-Products;Amines;Aromatics;Heterocycles
Mol File:    175013-18-0.mol

Melting point     63.7-65.2°
Boiling point     501.1±60.0 °C(Predicted)
density     1.27±0.1 g/cm3(Predicted)
storage temp.     0-6°C
pka    -0.23±0.10(Predicted)
form     neat
InChIKey    HZRSNVGNWUDEFX-UHFFFAOYSA-N
NIST Chemistry Reference    Pyraclostrobine(175013-18-0)
EPA Substance Registry System    Pyraclostrobin (175013-18-0)
Safety Information
Hazard Codes     N
Risk Statements     50/53
Safety Statements     60-61
RIDADR     UN3077 9/PG 3
WGK Germany     2
RTECS     EZ3441000
Hazardous Substances Data    175013-18-0(Hazardous Substances Data)
Toxicity    LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rainbow trout: 0.006 mg/l (Ammermann)
MSDS Information
Pyraclostrobin Usage And Synthesis
Uses    Pyraclostrobin is a fungicide for use in seed grass and food crops.
Uses    Agricultural fungicide.
Agricultural Uses    Pyraclostrobin (trade names: Cabrio®, Headline®) primed the tobacco cv. Xanthi nc for more rapid accumulation of antimicrobial PR-1 defence proteins after infection with Tobacco mosaic virus and the wildfire pathogen Ps pv. tabaci. The Pyraclostrobininduced priming for enhanced PR-1 accumulation in response to pathogen attack was associated with enhanced disease resistance (Herms et al. 2002). The enhanced resistance to pathogenic viruses and bacteria in Pyraclostrobin-treated plants was also seen on various crops and ornamental plants in both the greenhouse and field (Koehle et al. 2003, 2006). It is interesting that in the field, Pyraclostrobin-induced priming was associated with enhanced resistance also to abiotic stresses, including drought. In addition, treatment with Pyraclostrobin increased crop yield in the field. Also, in various crops Pyraclostrobin and other strobilurin fungicides induce a ‘greening effect.’ The term refers to the phenomenon of delayed leaf senescence and an increased grain-filling period resulting in enhanced biomass and yield (Bartlett et al. 2002). Together, the findings made with Pyraclostrobin suggest that this chemistry, in addition to exerting direct antifungal activity, may also protect plants by priming them for a boosted activation of subsequently stress-induced defence responses. This conclusion is consistent with an earlier report demonstrating that another commercial fungicide, Oryzemate®, enhanced the resistance to Tobacco mosaic virus in tobacco (Koganezawa et al. 1998) and to a bacterial and an oomycete pathogen in Arabidopsis (Yoshioka et al. 2001). Oryzemate® contains Probenazole as the active ingredient which is metabolized to saccharin in treated plants (Koganezawa et al. 1998). The latter compound seems to elicit priming in Oryzemate®-treated plants (Siegrist et al. 1998).