1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one CAS NO.196597-78-1

Product Name:    1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one
Synonyms:    1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one;1,2,6,7-Tetrahydro-8H-indeno[5,4-β]furan-8-one;RaMelteon I;4-b]furan-8-one;7-tetrahydro-;8H-Indeno[5;1,2,6,7-tetrahydroindeno[5,4-b]furan-8-one;Ramelteon Intermediate 1
CAS:    196597-78-1
MF:    C11H10O2
MW:    174.2
EINECS:    1308068-626-2                 
Mol File:    196597-78-1.mol

Melting point     149-1510C
Boiling point     334.2±42.0 °C(Predicted)
density     1.288±0.06 g/cm3(Predicted)
storage temp.     Sealed in dry,Room Temperature
CAS DataBase Reference    196597-78-1(CAS DataBase Reference)
Safety Information
HazardClass     IRRITANT
MSDS Information
1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Usage And Synthesis
Chemical Properties    White Solid
Uses    A tricyclic indan derivative as receptor agonist; a therapeutic agent for sleep disorders
1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Preparation Products And Raw materials
Raw materials    8H-Indeno[5,4-b]furan-8-one, 6,7-dihydro--->1-(2,3-dihydrobenzofuran-4-yl)ethanone-->Ethyl 3-(2,3-Dihydrobenzofuran-5-yl)propenoate-->2,3-Dihydrobenzo[b]furan-5-carbaldehyde-->3-(2,3-DIHYDRO-BENZOFURAN-5-YL)-PROPIONIC ACID ETHYL ESTER-->3-(6,7-Dibromo-2,3-dihydrobenzofuran-5-yl)propanoic Acid-->4,5-Dibromo-1,2,6,7-tertahydro-8H-indeno[5,4-b]furan-8-one-->(2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOIC ACID-->Ethyl 3-(6,7-Dibromo-2,3-dihydro-1-benzofuran-5-yl)propanoate-->Ethyl 3-(7-Bromo-2,3-dihydro-1-benzofuran-5-yl)propanoate-->6-Hydroxy-1-indanone-->Formaldehyde-->2,3-Dihydrobenzofuran
Preparation Products    Ramelteon-->2H-Indeno[5,4-b]furan, 1,6,7,8-tetrahydro--->2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-ylethylamine