2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine CAS NO.230615-51-7

Product Name:    2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
Synonyms:    2-trifluoro-1-(1;5-Methano-3H-3-benzazepin-3-yl)-;5-tetrahydro-1;Ethanone,2,2,2-thrifluoro-1-(1,2,4,5-tetrahydro -1,5-Methano-3H-3-benzapin-3-yl);1-(10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoro-ethanone;1-(10-Aza-tricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoro-ethanone;Ethanone, 2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-1,5-methano-3H-3-benzazepin-3-yl)-;2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine
CAS:    230615-51-7
MF:    C13H12F3NO
MW:    255.24
EINECS:    
Product Categories:    
Mol File:    230615-51-7.mol

2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine Chemical Properties
Melting point     67-68 ºC
Boiling point     381.7±42.0 °C(Predicted)
density     1.333
storage temp.     Sealed in dry,Room Temperature
pka    -1.82±0.20(Predicted)
Safety Information
HS Code     2933998090
MSDS Information
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine Usage And Synthesis
Uses    2,3,4,5-tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine is a reactant used in the preparation of Varenicline, a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine Preparation Products And Raw materials
Raw materials    357425-93-5-->10-AZA-TRICYCLO[6.3.1.0]DODECA-2,4,6-TRIENE TOSYLATE-->2,3,4,5-TETRAHYDRO-1H-1,5-METHANO-3-BENZAZEPINE HYDROCHLORIDE-->Trifluoroacetic anhydride
Preparation Products    2,3,4,5-Tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine