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REGADENOSON CAS NO.313348-27-5
- Min.Order: 1 Gram
- Payment Terms: T/T,MoneyGram,Other
- Product Details
Keywords
- REGADENOSON
- 313348-27-5
- 99% purity
Quick Details
- ProName: REGADENOSON
- CasNo: 313348-27-5
- Molecular Formula: C15H18N8O5
- Appearance: powder
- Application: intermediate
- DeliveryTime: in stock
- PackAge: According to the need of packing
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99% purity
- Storage: Keep in dark place,Sealed in dry,2-8°C
- Transportation: air,sea,courier
- LimitNum: 1 Gram
- Grade: Industrial Grade,Pharma Grade,Electron...
Superiority
Product Name: REGADENOSON
Synonyms: CS-1874;LEXISCAN; CVT-3146;;Regadenoson Impurity;Regadenoson Impurity 16;Regadenoson Impurity 18;Regadenoson(CVT-3146);6-Amino-2-[4-(methylcarbamoyl)-1H-pyrazol-1-yl]purine-9-yl-beta-D-ribofuranoside Regadenoson;Regadenoson 6-Amino-2-[4-(methylcarbamoyl)-1H-pyrazol-1-yl]purine-9-yl-beta-D-ribofuranoside
CAS: 313348-27-5
MF: C15H18N8O5
MW: 390.35
EINECS:
Product Categories: Inhibitors;Bases & Related Reagents;Nucleotides and Nucleosides;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
Mol File: 313348-27-5.mol
Details
Melting point 158-160°C
density 1.98±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
pka 13.07±0.70(Predicted)
CAS DataBase Reference 313348-27-5
Description Lexiscan ™(regadenoson) is an injectable adenosine A2A receptor agonist for use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies in patients unable to undergo adequate exercise induced stress. Regadenoson is the first adenosine A2A receptor agonist shown to be safe and effective as a pharmacologic stress agent in MPI studies. It is delivered as a rapid bolus (approximately 10 seconds) with no dose adjustment required for body weight. The product was developed under a license and collaboration agreement between CV Therapeutics and Astellas, and was launched by Astellas in June of 2008.
Chemical Properties Off-White Solid
Uses A selective A2A adenosine receptor agonist in myocardial imaging
Uses Regadenoson is a selective, short-acting adenosine A2A receptor agonist (Ki = 1.1 nM for pig striatum A2A receptor). It increases coronary blood flow 3.4- to 3.8-fold with a half-time to reversal of 1.9-2.6 minutes in open-chest anesthetized pigs. Regadenoson is used to induce hyperemia (increased blood flow), particularly in the context of myocardial perfusion imaging. It has also been found to increase the delivery of compounds to the central nervous system through the blood-brain barrier in animals.