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Home > Products >  4-Chloro-4'-hydroxybenzophenone

4-Chloro-4'-hydroxybenzophenone CAS NO.42019-78-3

  • Min.Order: 1 Gram
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Keywords

  • 4-Chloro-4'-hydroxybenzophenone
  • 42019-78-3
  • 98% purity

Quick Details

  • ProName: 4-Chloro-4'-hydroxybenzophenone
  • CasNo: 42019-78-3
  • Molecular Formula: C13H9ClO2
  • Appearance: powder
  • Application: intermediate
  • DeliveryTime: in stock
  • PackAge: accroding to the need
  • Port: Shanghai Port
  • ProductionCapacity: 100 Kilogram/Day
  • Purity: 98% purity
  • Storage: Sealed in dry,Room Temperature
  • Transportation: air,sea and courier
  • LimitNum: 1 Gram
  • Grade: Industrial Grade,Pharma Grade,Electron...

Superiority

Product Name:    4-Chloro-4'-hydroxybenzophenone
Synonyms:    4-hydroxy-4’-chloro-benophenone;Fenofibrate Impurity Ⅰ:4-Chloro-4'-hydroxybenzophenone;4-Chloro-4'-Hydroxybenzophenone 4-Hydroxy-4'-Chlorobenzophenone;4-p-Chlorobenzoylphenol;4-(4-Chlorobenzoyl)-4-Hydroxypiperidine;4-(4-CHLOROBENZOYL)PHENOL;4-Chloro-4'-hydroxybenzophenon;LABOTEST-BB LT00248477
CAS:    42019-78-3
MF:    C13H9ClO2
MW:    232.66
EINECS:    255-627-4                
Mol File:    42019-78-3.mol                           
                 

Details

Melting point     177-181 °C
Boiling point     257 °C (13 mmHg)
density     1.2082 (rough estimate)
refractive index     1.5434 (estimate)
Fp     100 °C
storage temp.     Inert atmosphere,Room Temperature
pka    7.68±0.15(Predicted)
form     neat
BRN     2049956
CAS DataBase Reference    42019-78-3(CAS DataBase Reference)
NIST Chemistry Reference    Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-(42019-78-3)
Safety Information
Hazard Codes     Xi,Xn
Risk Statements     36/37/38-20/21/22
Safety Statements     24/25-37/39-26-36
Hazard Note     Irritant
HS Code     29144000
MSDS Information
Provider    Language
(4-Chlorophenyl)(4-hydroxyphenyl)-Methanone    English
ACROS    English
ALFA    English
4-Chloro-4'-hydroxybenzophenone Usage And Synthesis
Chemical Properties    light grey to beige-brown powder
Uses    The Impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor
Preparation    Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
in the presence of trifluoromethanesulfonic acid at 45–55° (94%).
4-Chloro-4'-hydroxybenzophenone Preparation Products And Raw materials
Raw materials    Aluminum chloride-->Anisole-->4-Chlorobenzoyl chloride-->4-Chlorophenylacetylene-->4-chloro-4'-methoxybenzophenone-->SYN-BENZALDEHYDE OXIME-->4-chloro-4'-fluorobenzophenone-->4-CHLORO-4'-NITROBENZOPHENONE
Preparation Products    Fenofibric acid
 

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