β-ESTRADIOL CAS NO.50-28-2

β-ESTRADIOL Basic information

Product Name:    β-ESTRADIOL
Synonyms:    BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;β-Estradiol, 99% (dry wt.), ca 3% water;1,3,5-Estratriene-3,17beta-diol;17beta-Estradiol;3,17beta-Dihydroxy-1,3,5(10)-estratriene;Dihydrofolliculin;Estradiol
CAS:    50-28-2
MF:    C18H24O2
MW:    272.39
EINECS:    200-023-8
Product Categories:  
Mol File:    50-28-2.mol

β-ESTRADIOL Chemical Properties
Melting point     178-179 °C(lit.)
alpha     D25 +76 to +83° (dioxane)
Boiling point     355.44°C (rough estimate)
density     1.0708 (rough estimate)
refractive index     80.4 ° (C=1, Dioxane)
Fp     2℃
storage temp.     room temp
solubility     Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form     powder
pka    pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
color     White to off-white
Water Solubility     Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck     14,3703
BRN     1914275
Stability:    Stable. Incompatible with strong oxidizing agents.
InChIKey    VOXZDWNPVJITMN-ZBRFXRBCSA-N
CAS DataBase Reference    50-28-2(CAS DataBase Reference)
NIST Chemistry Reference    Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry System    Estradiol (50-28-2)

Safety Information
Hazard Codes     T,Xn,F
Risk Statements     60-61-45-63-64-40-36-20/21/22-11-48
Safety Statements     53-22-36/37/39-45-36/37-26-16-36-20
RIDADR     2811
WGK Germany     3
RTECS     KG2975000
F     8-10
HazardClass     6.1
PackingGroup     III
HS Code     29372390
Hazardous Substances Data    50-28-2(Hazardous Substances Data)
Toxicity    LD50 subcutaneous in rat: > 300mg/kg