3'-Methylacetanilide CAS NO.537-92-8

Product Name:    3'-Methylacetanilide
Synonyms:    n-(3-methylphenyl)-acetamid;N-(3-Methylphenyl)acetamide;N-(3-methylphenyl)-Acetamide;N-Acetyl-3-methylaniline;N-m-Tolylacetamide;ACETYL-M-TOLUIDINE;3'-METHYLACETANILIDE;3-METHYLACETANILIDE
CAS:    537-92-8
MF:    C9H11NO
MW:    149.19
EINECS:    208-678-1              
Mol File:    537-92-8.mol
                                                   

3'-Methylacetanilide Chemical Properties               
Melting point     65-67 °C (lit.)         
Boiling point     303 °C (lit.)              
density     1.1410                                          
vapor pressure     16 mm Hg ( 163 °C)
refractive index     1.5279 (estimate)
storage temp.     Inert atmosphere,Room Temperature
solubility     alcohol: freely soluble(lit.)
pka    15.12±0.70(Predicted)
Merck     14,74
Stability:    Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference    537-92-8(CAS DataBase Reference)
NIST Chemistry Reference    N-(3-Tolyl)acetic acid amide(537-92-8)
EPA Substance Registry System    m-Acetotoluidide (537-92-8)
Safety Information
Hazard Codes     Xn,Xi
Risk Statements     22-36/37/38
Safety Statements     26-36
WGK Germany     3
RTECS     AN2875000
HS Code     29242998
Toxicity    LD50 orl-mus: 1450 mg/kg TXAPA9 19,20,71
MSDS Information
Provider    Language
3'-Methylacetanilide    English
SigmaAldrich    English
3'-Methylacetanilide Usage And Synthesis
Chemical Properties    white crystalline solid
General Description    White solid.
Air & Water Reactions    Water insoluble.
Reactivity Profile    3'-Methylacetanilide is an amide. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard    ACUTE/CHRONIC HAZARDS: When heated to decomposition 3'-Methylacetanilide emits toxic fumes of nitrogen oxides.
Fire Hazard    Flash point data for 3'-Methylacetanilide are not available; however, 3'-Methylacetanilide is probably combustible.
Safety Profile    Moderately toxic by ingestion. Seealso p-ACETOTOLUIDIDE. When heated todecomposition it emits toxic fumes of NOx.
Purification Methods    Crystallise the toluidide from H2O, EtOH, aqueous EtOH or Et2O/pet ether (m 66o). UV: max 245nm (EtOH). [Beilstein 12 H 860, 12 I 400, 12 II 468, 12 III 1962, 12 IV 1823.]
3'-Methylacetanilide Preparation Products And Raw materials
Preparation Products    2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline-->4-Bromo-3-methylaniline