Cyclosporin A CAS NO.59865-13-3

Cyclosporin A Chemical Properties
Melting point     148-151°C
alpha     D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Boiling point     838.63°C (rough estimate)
density     0.9913 (rough estimate)
refractive index     1.6500 (estimate)
Fp     87℃
storage temp.     2-8°C
solubility     ethanol: 30 mg/mL
pka    13.32±0.70(Predicted)
form     solid
color     white
Water Solubility     Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck     14,2752
BRN     3647785
InChIKey    PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference    59865-13-3(CAS DataBase Reference)
IARC    1 (Vol. 50, 100A) 2012
EPA Substance Registry System    Cyclosporin A (59865-13-3)          

Cyclosporin A Basic information
Immunosuppressants Pharmacological effects Pharmacokinetics Indications Drug interactions Side effects Chemical properties Production methods
Product Name:    Cyclosporin A
Synonyms:    ol27-400;s7481f1;sandimmun;sandimmune;Cyclospori;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone;Cipol N
CAS:    59865-13-3
MF:    C62H111N11O12
MW:    1202.61
EINECS:    611-907-1
Mol File:    59865-13-3.mol
 Safety Information
Hazard Codes     T,Xn,F
Risk Statements     45-60-22-40-36-20/21/22-11
Safety Statements     53-45-36/37-24/25-22-26-16
RIDADR     UN 1648 3 / PGII
WGK Germany     3
RTECS     GZ4120000
HS Code     29419090
Hazardous Substances Data    59865-13-3(Hazardous Substances Data)
Toxicity    LD50 in mice, rats, rabbits (mg/kg): 107, 25, >10 i.v.; 2329, 1480, >1000 orally (Ryffel)