(R)-(+)-2-BROMOPROPIONIC ACID CAS NO.10009-70-8

Product Name:    (R)-(+)-2-BROMOPROPIONIC ACID
Synonyms:    PROPANOIC ACID, 2-BROMO-, (2R)-;(R)-(+)-2-BROMOPROPIONIC ACID;2-R-(+) bromopropionic acid;(R)-(+)-2-Bromopropionic acid, GC 98%;(R)-(+)-2-BROMOPROPIONIC ACID 98+%;(R)-(+)-2-Bromopropionic acid, >85% ee, 99%;(R)-(+)-2-Bromopropionic acid, 99%, ee:>85%;(R)-2-Bromopropanoic acid
CAS:    10009-70-8
MF:    C3H5BrO2
MW:    152.97
EINECS:                  
Mol File:    10009-70-8.mol
 

Melting point     25°C
Boiling point     203 °C
density     1.692 g/mL at 20 °C (lit.)
refractive index     n20/D 1.475
Fp     100 °C
storage temp.     2-8°C
pka    3.00±0.10(Predicted)
optical activity    [α]20/D +26±2°, neat
BRN     1720262
Safety Information
Hazard Codes     C
Risk Statements     22-34
Safety Statements     26-36/37/39-45
RIDADR     UN 3265 8/PG 3
WGK Germany     3
F     10
HazardClass     8
PackingGroup     III
HS Code     29159000
MSDS Information
Provider    Language
SigmaAldrich    English
ACROS    English
(R)-(+)-2-BROMOPROPIONIC ACID Usage And Synthesis
Chemical Properties    clear colorless to light brown liquid
Purification Methods    Dissolve it in Et2O, dry (CaCl2), evaporate and distil it through a short column. Distillation through a Podbielniak column (p 11) (see S-(-)-2-chloropropionic acid below) led to decomposition. Store it in the dark under N2, preferably in sealed ampoules. Even at -10o it slowly decomposes. [Fuet et al. J Am Chem Soc 76 6054 1954, Beilstein 2 IV 761.]
(R)-(+)-2-BROMOPROPIONIC ACID Preparation Products And Raw materials
Raw materials    [R,(+)]-2-Bromopropanoic acid methyl ester-->(S)-2-((Methylsulfonyl)oxy)propanoic acid-->L-Alanine-->Cinchonine-->2-Bromopropionic acid-->D-Alanine
Preparation Products    (S)-(-)-2-BROMOPROPIONIC ACID