Icariins CAS NO.105102-22-5

Mometasone Basic information
Product Name:    Mometasone
Synonyms:    icariins;Mometasone (Mometasone Furoate EP Impurity G);MOMETASONE;9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;MometasoneFuroateBase;Mometasone Furoate EP Impurity G/Mometasone;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI)
CAS:    105102-22-5
MF:    C22H28Cl2O4
MW:    427.36
EINECS:    818-819-4
Product Categories:    
Mol File:    105102-22-5.mol
Mometasone Structure
Mometasone Chemical Properties
Melting point     >211oC (dec.)
Boiling point     586.6±50.0 °C(Predicted)
density     1.35±0.1 g/cm3(Predicted)
storage temp.     Refrigerator, Under Inert Atmosphere
solubility     DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka    12.08±0.70(Predicted)
form     Solid
color     White to Pale Beige
InChIKey    WOFMFGQZHJDGCX-MCUOXHNDNA-N
SMILES    [C@]1(OC(=O)C2OC=CC=2)([C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C(CCl)=O |&1:0,9,12,14,24,26,28,31,r|
CAS DataBase Reference    105102-22-5(CAS DataBase Reference)
Safety Information
MSDS Information
Mometasone Usage And Synthesis
Chemical Properties    Pale Yellow Solid
Uses    Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. It can be applied to the skin, inhaled, or used in the nose. It is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis. Mometasone furoate, not mometasone, is used in medical products.
Definition    ChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.
Side effects    The most common side effects are an unpleasant smell and a dry or sore nose or throat.

Mometasone Basic information
Product Name:    Mometasone
Synonyms:    icariins;Mometasone (Mometasone Furoate EP Impurity G);MOMETASONE;9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;MometasoneFuroateBase;Mometasone Furoate EP Impurity G/Mometasone;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI)
CAS:    105102-22-5
MF:    C22H28Cl2O4
MW:    427.36
EINECS:    818-819-4
Product Categories:    
Mol File:    105102-22-5.mol
Mometasone Structure
Mometasone Chemical Properties
Melting point     >211oC (dec.)
Boiling point     586.6±50.0 °C(Predicted)
density     1.35±0.1 g/cm3(Predicted)
storage temp.     Refrigerator, Under Inert Atmosphere
solubility     DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka    12.08±0.70(Predicted)
form     Solid
color     White to Pale Beige
InChIKey    WOFMFGQZHJDGCX-MCUOXHNDNA-N
SMILES    [C@]1(OC(=O)C2OC=CC=2)([C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C(CCl)=O |&1:0,9,12,14,24,26,28,31,r|
CAS DataBase Reference    105102-22-5(CAS DataBase Reference)
Safety Information
MSDS Information
Mometasone Usage And Synthesis
Chemical Properties    Pale Yellow Solid
Uses    Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. It can be applied to the skin, inhaled, or used in the nose. It is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis. Mometasone furoate, not mometasone, is used in medical products.
Definition    ChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.
Side effects    The most common side effects are an unpleasant smell and a dry or sore nose or throat.