GLYX 13 CAS NO.117928-94-6

GLYX13

英文同义词L-ThreoninaMide,L-threonyl-L-prolyl-L-prolyl-;GLYX-13trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamidetrifluorChemicalbookoacetate;GLYX13;Thr-Pro-Pro-Thr-NH2trifluoroacetate;TPPT-amidetrifluoroacetate;Rapastinel;GIYX-13

CAS号117928-94-6

分子式C18H31N5O6

分子量413.47

沸点844.2±65.0°C(Predicted)

密度1.370±0.06g/cm3(Predicted)储存条件Keepindarkplace,Inertatmosphere,Storeinfreezer,under-20°C

溶解度DMChemicalbookF：25mg/mL；

DMSO：15mg/mL；

乙醇：10mg/mL；

PBS（pH7.2）：5mg/mL

形态粉末

酸度系数(pKa)12.26±0.45(Predicted)

颜色白色至棕褐色水溶解性Solubleto2mg/mlinwater

Rapatinib is an NMDAR(N-methyl-D-aspartate receptor) modulator with partial agonist properties. Rapastinel is a new antidepressant drug approved as an adjunct treatment for treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-oral) Chemicalbook amideated tetrapeptide that acts as a selective, weak local agonist (mixed antagonist/agonist) at the glycine site of the NMDA receptor complex (Emax25%). The drug is a fast, long-acting antidepressant with the ability to inhibit and enhance NMDA receptor-mediated signal transduction, and is a powerful intellectual enhancer.

Rapatinib is an NMDAR(N-methyl-D-aspartate receptor) modulator with partial agonist properties. Rapastinel is a new antidepressant drug approved as an adjunct treatment for treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-oral) Chemicalbook amideated tetrapeptide that acts as a selective, weak local agonist (mixed antagonist/agonist) at the glycine site of the NMDA receptor complex (Emax25%). The drug is a fast, long-acting antidepressant with the ability to inhibit and enhance NMDA receptor-mediated signal transduction, and is a powerful intellectual enhancer.

GLYX13

英文同义词L-ThreoninaMide,L-threonyl-L-prolyl-L-prolyl-;GLYX-13trifluoroacetate;L-Threonyl-L-prolyl-L-prolyl-L-threoninamidetrifluorChemicalbookoacetate;GLYX13;Thr-Pro-Pro-Thr-NH2trifluoroacetate;TPPT-amidetrifluoroacetate;Rapastinel;GIYX-13

CAS号117928-94-6

分子式C18H31N5O6

分子量413.47

沸点844.2±65.0°C(Predicted)

密度1.370±0.06g/cm3(Predicted)储存条件Keepindarkplace,Inertatmosphere,Storeinfreezer,under-20°C

溶解度DMChemicalbookF：25mg/mL；

DMSO：15mg/mL；

乙醇：10mg/mL；

PBS（pH7.2）：5mg/mL

形态粉末

酸度系数(pKa)12.26±0.45(Predicted)

颜色白色至棕褐色水溶解性Solubleto2mg/mlinwater