Tylosin CAS NO.1401-69-0

Tylosin Basic information

Product Name:    Tylosin
Synonyms:    TYLOCINE(R);TYLOSIN;fradizine;tylocine;Tylosine;TYLAN50;Tylosin (base and/or unspecified salts);N,N-Tylozine
CAS:    1401-69-0
MF:    C46H77NO17
MW:    916.1
EINECS:    215-754-8
Product Categories:    
Mol File:    1401-69-0.mol

Tylosin Chemical Properties
Melting point     135-137°C
alpha     D25 -46° (c = 2 in methanol)
Boiling point     796.05°C (rough estimate)
density     1.1424 (rough estimate)
refractive index     1.5280 (estimate)
storage temp.     Sealed in dry,2-8°C
pka    pKa 7.73(H2O t = 25 I = 0.167) (Uncertain)
Water Solubility     H2O: soluble 50 mg/mL
Stability:    Solutions are stable at pH 4-9 (most stable at pH 7);
Below pH 4 tylosin B (desmycosin) is formed as a result of acid hydrolysis;
In neutral and alkaline pH – tylosin aldol (TAD) is formed together with polar degradation products of unknown identity;
When tylosin solution is exposed to daylight, a photodegradation product - isotylosin A (isoTA) is formed.
EPA Substance Registry System    Tylosin (1401-69-0)

Safety Information
Hazard Codes     Xn,N
Risk Statements     42/43-50
Safety Statements     36-61-45-36/37-22
HS Code     2941906000
Hazardous Substances Data    1401-69-0(Hazardous Substances Data)
Toxicity    Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog.