Rasagiline mesylate CAS NO.161735-79-1

Product Name:    Rasagiline mesylate
Synonyms:    (1R)-2,3-Dihydro-N-2-propynyl-1H-inden-1-amine methanesulfonate;CS-289;R-(+)-Rasagiline mesylate;N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine methanesulfonate;Rasagiline Mesylate/Tartrate/Base;(1R)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine Mesylate;(R)-N-2-Propynyl-1-indanamine Mesylate;Agilect
CAS:    161735-79-1
MF:    C13H17NO3S
MW:    267.34398
EINECS:    694-423-3
Product Categories:    Chiral;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Rasagiline;Signalling;APIs
Mol File:    161735-79-1.mol

Melting point     155-158°C
storage temp.     2-8°C
solubility     H2O: ≥20mg/mL
form     powder
color     white to tan
optical activity    [α]/D +15 to +28°, c = 0.6 mg/mL in H2O
CAS DataBase Reference    161735-79-1(CAS DataBase Reference)
Safety Information
Hazard Codes     Xn
Risk Statements     22
Safety Statements     24/25
WGK Germany     3
HS Code     29214990

Description    Rasagiline mesylate is a potent and selective irreversible monoamine oxidase B (MAO-B) inhibitor launched in 2005 in Israel by Teva as monotherapy in patients with early Parkinson's disease and as adjuvant treatment in moderate-toadvanced disease. Lundbeck will market the drug throughout Europe. Rasagiline is in phase II clinical trials at Teva and Eisai for the treatment of Alzheimer's type dementia.
Chemical Properties    White to Off-White Crystalline Solid
Uses    A selective irreversible MAO-B inhibitor. Antiparkinsonian
Uses    Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.
Uses    Rasagiline is a selective irreversible MAO-B inhibitor. Rasagiline is an Antiparkinsonian agent.