10-formyldihydrofolate In Stock CAS NO.28459-40-7

10-formyldihydrofolate Basic information
Product Name:    10-formyldihydrofolate
Synonyms:    Folinic Acid IMpurity F;Folic acid IMpurity F;10-ForMyl-7,8-dihydro Folic Acid (>85%) DisodiuM Salt;C20H21N7O7;10-ForMyl-7;10-formyldihydrofolic acid;L-Glutamic acid,N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-;10-Formyl-7,8-dihydro Folic Acid Disodium Salt
CAS:    28459-40-7
MF:    C20H21N7O7
MW:    471.43
EINECS:    
Product Categories:    Amines, Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:    28459-40-7.mol

10-formyldihydrofolate Chemical Properties
density     1.67±0.1 g/cm3(Predicted)
solubility     Aqueous Acid (Slightly), Aqueous Base (Slightly)
pka    3.38±0.10(Predicted)
form     Solid
color     Orange to Very Dark Brown
Stability:    Hygroscopic, Temperature Sensitive

10-formyldihydrofolate Usage And Synthesis
Uses    10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
Definition    ChEBI: 10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-).