2,5-Difluorobenzoic acid CAS NO.2991-28-8

Product Name:    2,5-Difluorobenzoic acid
Synonyms:    2,5-DIFLUOROBENZOIC ACID;RARECHEM AL BO 0019;Benzoic acid, 2,5-difluoro-;2,5-Difluorobenzic acid;2-chloro-6-flurobenzyl cyanide;2,5-Difluorobenzoic;2,5-Difluorobenzoic acid 98%;2,5-Difluorobenzoicacid98%
CAS:    2991-28-8                        
MF:    C7H4F2O2           
MW:    158.1          
EINECS:    221-060-6                          
Mol File:    2991-28-8.mol                     

2,5-Difluorobenzoic acid Chemical Properties
Melting point     132-134 °C (lit.)
Boiling point     244.7±20.0 °C(Predicted)
density     1.3486 (estimate)
storage temp.     Sealed in dry,Room Temperature
solubility     acetone: soluble25mg/mL, clear, faintly yellow
pka    2.93±0.10(Predicted)
Water Solubility     Insoluble in water.
BRN     973351
InChIKey    LBQMIAVIGLLBGW-UHFFFAOYSA-N
CAS DataBase Reference    2991-28-8(CAS DataBase Reference)
NIST Chemistry Reference    2,5-Difluorobenzoic acid(2991-28-8)
EPA Substance Registry System    Benzoic acid, 2,5-difluoro- (2991-28-8)
Safety Information
Hazard Codes     Xi
Risk Statements     36/37/38
Safety Statements     26-37/39
WGK Germany     3
Hazard Note     Irritant
HazardClass     IRRITANT
HS Code     29163990
MSDS Information
Provider    Language
2,5-Difluorobenzoic acid    English
SigmaAldrich    English
ACROS    English
ALFA    English
2,5-Difluorobenzoic acid Usage And Synthesis
Chemical Properties    white crystalline powder
Synthesis Reference(s)    Journal of Medicinal Chemistry, 28, p. 1864, 1985 DOI: 10.1021/jm00150a018
2,5-Difluorobenzoic acid Preparation Products And Raw materials
Raw materials    2,3,4,6-TETRAFLUOROBENZOIC ACID-->2',5'-Difluoroacetophenone-->1-Bromo-2,5-difluorobenzene-->CARBON DIOXIDE-->1,2,4-Trifluorobenzene-->1,2,3,5-Tetrafluorobenzene-->1,4-Difluorobenzene
Preparation Products    Solvent Violet 9-->3-Fluorobenzoic acid