Etoposide CAS NO.33419-42-0

Etoposide Basic information
Pharmacological effects Side effects Contraindications Uses Usage and Dosage Precautions Drug Interactions

Product Name:    Etoposide
Synonyms:    (-)-Etoposide, (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside;EtoposideETOPOSIDE
CAS:33419-42-0
MES-012;BMY-40481, Etoposide 4'-Dihydrogenphosphate, VP-16-213;Etoposide , 98.0%(LC);Etoposide for system suitability;GAL4 [(1-147) + VP16 (411-490)] from Saccharomyces cerevisiae human herpesvirus 2;Etoposide, >=98%;(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS:    33419-42-0
MF:    C29H32O13
MW:    588.56
EINECS:    251-509-1
Product Categories:    
Mol File:    33419-42-0.mol

Etoposide Chemical Properties
Melting point     236-251 °C (lit.)
alpha     D20 -110.5° (c = 0.6 in chloroform)
Boiling point     563.9°C (rough estimate)
density     1.2966 (rough estimate)
refractive index     -110.5 ° (C=0.6, CHCl3)
storage temp.     2-8°C
solubility     DMSO: 30 mg/mL
pka    9.8(at 25℃)
form     powder
color     white
Water Solubility     Insoluble in water.
Merck     14,3886
IARC    1 (Vol. 76, 100A) 2012, 1 (Vol. 76, 100A) 2012
EPA Substance Registry System    Etoposide (33419-42-0)

Safety Information
Hazard Codes     T,Xi
Risk Statements     45-22-36/37/38
Safety Statements     53-45-36/37-26
RIDADR     3249
WGK Germany     3
RTECS     KC0190000
HazardClass     6.1(a)
PackingGroup     II
HS Code     29389090
Hazardous Substances Data    33419-42-0(Hazardous Substances Data)
Toxicity    LD50 oral in rabbit: 147mg/kg