2-Dimethylaminoethyl chloride hydrochloride 4584-46-7 CAS NO.4584-46-7

Synonyms: N,N-Dimethylamino chloroethane hydrochloride;N,N-DIMETHYLAMINOETHYL CHLORIDE HYDROCHLORIDE;N,N-DIMETHYL-N-2-CHLOROETHYLAMMONIUM CHLORIDE;N-(2-CHLOROETHYL)-N,N-DIMETHYLAMMONIUM CHLORIDE;N-(2-CHLOROETHYL)DIMETHYLAMINE HYDROCHLORIDE;2-chloro-n,n-dimethyl-ethanaminhydrochloride;2-chloro-n,n-dimethyl-ethylaminhydrochloride;bis(methyl)-2-chloroethylaminehydrochloride
CAS: 4584-46-7
MF: C4H11Cl2N
MW: 144.04
EINECS: 224-970-1
Product Categories: Halogen compounds;For Chlorpheniramine's Production;Intermediates
Mol File: 4584-46-7.mol
2-Dimethylaminoethyl chloride hydrochloride Structure
2-Dimethylaminoethyl chloride hydrochloride Chemical Properties
Melting point  201-204 °C(lit.)
Water Solubility  2000 g/L (20 ºC)
Sensitive  Hygroscopic
BRN  3591234
CAS DataBase Reference 4584-46-7(CAS DataBase Reference)
EPA Substance Registry System Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride(4584-46-7)
Safety Information
Hazard Codes  T,N,T+
Risk Statements  22-24-36/37/38-68-51/53-26
Safety Statements  26-36/37-45-61-36/37/39-28A
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  KQ9020000
TSCA  Yes
HazardClass  6.1 
PackingGroup  III
HS Code  29211980

【Synonyms】

2-Chloroethyldimethylammonium chloride
2-Chloroethyl-dimethylazanium chloride
Bis(methyl)-2-chloroethylamine hydrochloride
Dimethyl(2-chloroethyl)amine hydrochloride
Dimethyl-beta-chloroethylamine hydrochloride
【CAS】

4584-46-7
【Formula】

C4H11Cl2N
【Molecular Weight】

144.04
【EINECS】

224-970-1
【RTECS】

KQ9020000
【RTECS Class】

Tumorigen; Mutagen; Primary Irritant
【Beilstein/Gmelin】

3591234
【Beilstein Reference】

3-04-00-00237
【EC Class】

toxic, irritant
Physical and Chemical Properties Back to Contents
【Appearance】

Off white crystalline powder.
【Vapor Density】

5
First Aid Measures Back to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】 

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage Back to Contents
【Storage】

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.
Hazards Identification Back to Contents
【Inhalation】

May cause respiratory tract irritation.
【Skin】

May cause skin irritation. Harmful if absorbed through the skin. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
【Eyes】

May cause eye irritation.
【Ingestion】

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
【EC Risk Phrase】

R 22 23/24 36/37/38 43
【EC Safety Phrase】

S 22 26 36/37/39 45
【UN (DOT)】

2811
Exposure Controls/Personal Protection Back to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】

Prolonged or repeated skin contact may cause dermatitis.
Fire Fighting Measures Back to Contents
【Autoignition】

220
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release Measures Back to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Stability and Reactivity Back to Contents
【Disposal Code】

3
【Incompatibilities】

Oxidizing agents.
【Stability】

Stable under normal temperatures and pressures.
【Decomposition】

Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Transport Information Back to Contents
【UN Number】

2811
【HS Code】

2921 19 80