Hydrocortisone acetate CAS NO.50-03-3

Hydrocortisone acetate Basic information

Product Name:    Hydrocortisone acetate
Synonyms:    (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;Cortisone Acetate EP Impurity A（Hydrocortisone Acetate）;Hydrocortisone Impurity 3（Hydrocortisone EP Impurity C）
CAS:    50-03-3
MF:    C23H32O6
MW:    404.5
EINECS:    200-004-4
Product Categories:    
Mol File:    50-03-3.mol
 

Hydrocortisone acetate Chemical Properties
Melting point     223 °C (dec.)(lit.)
alpha     D25 +166° (c = 0.4 in dioxane); D25 +150.7° (c = 0.5 in acetone)
Boiling point     446.1°C (rough estimate)
density     d420 1.289
refractive index     1.4593 (estimate)
Fp     223°C
storage temp.     0-6°C
solubility     Practically insoluble in water, slightly soluble in anhydrous ethanol and in methylene chloride
pka    12.42±0.70(Predicted)
Water Solubility     Insoluble in water.
Decomposition     223 ºC
Merck     14,4787
BRN     2066841
Stability:    Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference    50-03-3(CAS DataBase Reference)
NIST Chemistry Reference    Hydrocortisone acetate(50-03-3)

Safety Information
Hazard Codes     Xn,T
Risk Statements     63-10-45
Safety Statements     36/37-45-53
WGK Germany     3
RTECS     GM8960000
HS Code     29372100
Toxicity    LD50 intraperitoneal in mouse: 2300mg/kg