Indometacin CAS NO.53-86-1

Indometacin Basic information

Product Name:    Indometacin
Synonyms:    1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin methanol solution;indomethacin usp;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE
CAS:    53-86-1
MF:    C19H16ClNO4
MW:    357.79
EINECS:    200-186-5
Product Categories:    
Mol File:    53-86-1.mol
 

Indometacin Chemical Properties
Melting point     158-162 °C
Boiling point     499.4±45.0 °C(Predicted)
density     1.2135 (rough estimate)
refractive index     1.6800 (estimate)
storage temp.     Store at RT
solubility     ethanol: 50 mg/mL, clear, yellow-green
pka    4.5(at 25℃)
form     White to off-white powder
Water Solubility     Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Sensitive     Light Sensitive
Merck     14,4968
BRN     497341
Stability:    Stable. Incompatible with strong oxidizing agents.
InChIKey    CGIGDMFJXJATDK-UHFFFAOYSA-N
CAS DataBase Reference    53-86-1(CAS DataBase Reference)
NIST Chemistry Reference    Indomethacin(53-86-1)
EPA Substance Registry System    Indomethacin (53-86-1)

Safety Information
Hazard Codes     T+,Xi,T
Risk Statements     28-36/37/38-39/23/24/25-23/24/25
Safety Statements     28-36/37-45-36-26
RIDADR     UN 2811 6.1/PG 1
WGK Germany     3
RTECS     NL3500000
F     8-10
TSCA     Yes
HazardClass     6.1
PackingGroup     I
HS Code     29339900
Hazardous Substances Data    53-86-1(Hazardous Substances Data)
Toxicity    LD50 i.p. in rats: 13 mg/kg (Klaassen)