- Product Details
Keywords
- 53-86-1
- Thiabendazole
- pharmaceutical grade
Quick Details
- ProName: Thiabendazole
- CasNo: 53-86-1
- Molecular Formula: C19H16ClNO4
- Appearance: Crystalline Solid
- Application: Inhibits cyclooxygenase (IC50=0.1uM) s...
- DeliveryTime: instock
- PackAge: accroding to the need
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Day
- Purity: 99%
- Storage: cool and dry
- Transportation: air,sea and courier
- LimitNum: 1 Gram
Superiority
Indometacin Basic information
Product Name: Indometacin
Synonyms: AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE;INDOMETHACIN;INDOMETHACINE;LABOTEST-BB LT00244830;1-(P-CHLOROBENZYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
EINECS: 200-186-5
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Lipid signaling;INDOCIN;Other APIs
Mol File: 53-86-1.mol
Details
Indometacin Chemical Properties
mp 155-162 °C
storage temp. Store at RT
solubility ethanol: 50 mg/mL, clear, yellow-green
Merck 4968
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 53-86-1(CAS DataBase Reference)
NIST Chemistry Reference Indomethacin(53-86-1)
EPA Substance Registry System 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy- 2-methyl-(53-86-1)
Safety Information
Hazard Codes T+,Xi
Risk Statements 28-36/37/38
Safety Statements 28-36/37-45-36-26
RIDADR UN 2811 6.1/PG
WGK Germany
RTECS NL3500000
F 8-10
HazardClass 6.1
PackingGroup I
Hazardous Substances Data 53-86-1(Hazardous Substances Data)
Indometacin Usage And Synthesis
Chemical Properties Crystalline Solid
Usage Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD
Usage antiinflammatory, antipyretic, analgesic
General Description Crystals.
Air & Water Reactions Practically insoluble in water. Decomposes in alkali.
Reactivity Profile A weak organic acid.
Fire Hazard Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Biological Activity Cyclooxgenase (COX) inhibitor; displays selectivity for COX-1 (IC 50 values are 230 and 630 nM for human COX-1 and COX-2 respectively). Widely used anti-inflammatory agent.