DL-Mevalonolactone CAS NO.674-26-0

Product Name:    DL-Mevalonolactone
Synonyms:    DL-MEVALONOLACTONE;β-Hydroxy-β-methyl-δ-valerolactone, (±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, (±)-Mevalolactone, (±)-Mevalonic acid lactone, (±)-Mevalonolactone;(4S)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-3,5-Dihydroxy-3-methylpentanoic acid δ-lactone;(S)-4β-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one;Beta-Hydro;(±)-Mevalonolactone,(±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, DL-Mevalolactone, DL-Mevalonic acid lactone
CAS:    674-26-0
MF:    C6H10O3
MW:    130.14
EINECS:    211-615-0 
Mol File:    674-26-0.mol                              

Melting point     28 °C(lit.)
alpha     -1.0～+1.0°(20℃/D)(c=5, C2H5OH)
Boiling point     145-150 °C5 mm Hg(lit.)
density     1.1066 (rough estimate)
refractive index     n20/D 1.473(lit.)
Fp     >230 °F
storage temp.     -20°C
pka    13.57±0.20(Predicted)
Merck     14,6163
BRN     80960
Stability:    Hygroscopic
InChIKey    JYVXNLLUYHCIIH-UHFFFAOYSA-N
CAS DataBase Reference    674-26-0(CAS DataBase Reference)
NIST Chemistry Reference    Dl-mevalonic acid lactone(674-26-0)
Safety Information
WGK Germany     3
F     3-10
HS Code     29322090
MSDS Information
Provider    Language
SigmaAldrich    English
DL-Mevalonolactone Usage And Synthesis
Chemical Properties    Pale Yellow Oil
Uses    A metabolite from endophytes of the medicinal plant Erythrina crista-galli.
Uses    HMG CoA substrate
Synthesis Reference(s)    Journal of the American Chemical Society, 104, p. 5486, 1982 DOI: 10.1021/ja00384a040
Synthesis, p. 719, 1974 DOI: 10.1055/s-1974-23416
Purification Methods    Purify the lactone via the dibenzyl-ethylenediammonium salt (m 124-125o) [Hofmann et al. J Am Chem Soc 79 2316 1957], or by chromatography on paper or on a Dowex-1 (formate) column. [Bloch et al. J Biol Chem 234 2595 1959.] Store it as the N,N'-dibenzylethylenediamine (DBED) salt, or as the lactone in a sealed container at 0o. [Beilstein 18/1 V 19.]
DL-Mevalonolactone Preparation Products And Raw materials
Preparation Products    3-METHYLPENTANE-1,3,5-TRIOL