- Product Details
Keywords
- CILOPROST
- 6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-16-METHYL-PROSTA-5E,13E-DIEN-18-YN-1-OIC ACID
- Iloprost
Quick Details
- ProName: Iloprost
- CasNo: 73873-87-7
- Molecular Formula: C22H32O4
- Appearance: Solid
- Application: A synthetic analogue of Prostacyclin ...
- DeliveryTime: instock
- PackAge: accordingto the customer
- Port: shanghai
- ProductionCapacity: 100 Metric Ton/
- Purity: 99%
- Storage: Amber Vial, -20°C Freezer, Under inert...
- Transportation: by air sea courier
- LimitNum: 1 Gram
- Related Substances: 1
- Residue on Ignition: 1
- Heavy Metal: 1
- Valid Period: 1
- 1: 1
- 1: 1
Superiority
ChEBI: Iloprost is a carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension. It has a role as a platelet aggregation inhibitor and a vasodilator agent. It is a monocarboxylic acid, a secondary alcohol and a carbobicyclic compound.
Details
This more chemically and biologically stable derivativeof prostacyclin is available as a solution (10 μg/mL)for nasal inhalation (Ventavis by Actelion) via a preciselycalibrated inhalation device for the treatment of pulmonaryarterial hypertension (PAH). Patients inhale 6 to 8 puffs ofaerosolized iloprost every 2 to 3 hours to produce a directvasodilatory effect on pulmonary blood vessels, therebydecreasing vascular resistance. Side effects of coughing,flushing, headaches, and jaw pain have been most commonlyreported