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Cefmenoxime hydrochloride CAS NO.75738-58-8
- Min.Order: 1
- Payment Terms: T/T
- Available Specifications:
- Product Details
Keywords
- Cefmenoxime hydrochloride
- 75738-58-8
- 99%
Quick Details
- ProName: Cefmenoxime hydrochloride
- CasNo: 75738-58-8
- Molecular Formula: C32H35ClN18O10S6
- Appearance: white solid
- Application: INTERMEDITD
- DeliveryTime: In stock
- PackAge: According to ypur needs
- Port: Shang Hai
- ProductionCapacity: 100 Metric Ton/Year
- Purity: 99%
- Storage: under inert gas (nitrogen or Argon) at...
- Transportation: Courier Air Sea
- LimitNum: 1
Superiority
| Cefmenoxime hydrochloride Basic information |
| Product Name: | Cefmenoxime hydrochloride |
| Synonyms: | 8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride;7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride;Bestcall;Bestron;Cemix;SCE-1365(free acid);Tacef |
| CAS: | 75738-58-8 |
| MF: | C16H18ClN9O5S3 |
| MW: | 548.01 |
| EINECS: | 278-299-4 |
| Product Categories: | CEFMAX;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
| Mol File: | 75738-58-8.mol |
Details
| Cefmenoxime hydrochloride Chemical Properties |
| Melting point | >175°C (dec.) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| form | Solid |
| color | Off-White to Pale Yellow |
| InChIKey | HZYJYGJIOCXOTH-AJVJENPNNA-N |
| SMILES | C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r| |
| Safety Information |
| HS Code | 2941906000 |
| MSDS Information |
| Cefmenoxime hydrochloride Usage And Synthesis |
| Description | Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea. |
| Originator | Takeda (Japan) |
| Uses | A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis. |
| Uses | antibacterial |
| Definition | ChEBI: The hemihydrochloride salt of cefmenoxime. |
| Brand name | Cefmax (TAP);TACEF;BESTCALL. |
| General Description | Cefmenoxime was synthesized by Takeda Pharmaceutical Co. in 1978. It contains aminothiazole and methoxyimino groups in the 7-acyl position and a methyltetrazole group at the 3 position of the cephem nucleus. Cefmenoxime has a wide activity spectrum against gram-positive and gram-negative bacteria, including anaerobes, except Staphylococcus aureus. Cefmenoxime is a member of the so-called third-generation cephalosporins, a recently introduced class of clinically important antibiotics. |