PHENFORMIN HCL 834-28-6 CP2015 CAS NO.834-28-6

Product Name: Phenformin hydrochloride
Synonyms: PHENFORMIN HCL;PHENFORMIN HYDROCHLORIDE;PHENETHYLBIGUANIDE HYDROCHLORIDE;1-phenethylbiguanide hydrochloride;1-fenetilbiguanidecloridrato;1-phenethyl-biguanidhydrochloride;1-phenethyl-biguanidmonohydrochloride;1-phenylaethylbiguanidhydrochlorid
CAS: 834-28-6
MF: C10H16ClN5
MW: 241.72
EINECS: 212-637-3
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API;VIAGRA;Inhibitors
Mol File: 834-28-6.mol
Phenformin hydrochloride Structure
Phenformin hydrochloride Chemical Properties
Melting point  175-178°C
storage temp.  -20°C Freezer
Water Solubility  >=10 g/100 mL at 21 ºC
CAS DataBase Reference 834-28-6(CAS DataBase Reference)
EPA Substance Registry System Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride(834-28-6)
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  DU2200000

Chemical Properties White Crystalline Solid
Usage It is an anti-diabetic drug from the biguanide class
Usage erectile dysfunction therapy
General Description White solid or powder. Formerly used as an anti-diabetic drug. Toxic (causes lactic acidosis.
Air & Water Reactions Water soluble.
Reactivity Profile Phenformin hydrochloride gives weakly acidic aqueous solutions. May react with strong oxidizing agents.
Fire Hazard Flash point data for Phenformin hydrochloride are not available; however, Phenformin hydrochloride is probably combustible.

【Product Name】

1-Phenethylbiguanide hydrochloride
【Synonyms】

1-(2-Phenylethyl)biguanide hydrochloride
Glucopostin
Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
Meltrol
Phenethylbiguanide hydrochloride
Phenformin hydrochloride
【CAS】

834-28-6
【Formula】

C10H16ClN5
【Molecular Weight】

241.72
【EINECS】

212-637-3
【RTECS】

DU2200000
【RTECS Class】

Drug; Mutagen
【Beilstein/Gmelin】

3636147
【Beilstein Reference】

4-12-00-02472
Physical and Chemical Properties Back to Contents
【Appearance】

White solid or powder.
【Melting Point】

175 - 178
【Density】

1.26 g/cm3
First Aid Measures Back to Contents
【Ingestion】

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
【Inhalation】

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
【Skin】

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
【Eyes】

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Handling and Storage Back to Contents
【Storage】

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards Identification Back to Contents
【Ingestion】

See inhalation.
【Inhalation】

Symptoms of exposure to this compound include metallic taste, nausea, anorexia, vomiting, diarrhea, cramps, weight loss and weakness.
【Skin】

See inhalation.
【Eyes】

See inhalation
Exposure Controls/Personal Protection Back to Contents
【Personal Protection】

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
【Respirators】

Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Fire Fighting Measures Back to Contents
【Fire Fighting】

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
【Fire Potential】

This material is probably combustible.
Accidental Release Measures Back to Contents
【Small spills/leaks】

If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability and Reactivity Back to Contents
【Incompatibilities】

May react with strong oxidizing agents.
【Stability】

No data.