- Product Details
Keywords
- S)-3-Hydroxypyrrolidine
- 100243-39-8
- 98% purity
Quick Details
- ProName: S)-3-Hydroxypyrrolidine
- CasNo: 100243-39-8
- Molecular Formula: C4H9NO
- Appearance: powder
- Application: intermediate
- DeliveryTime: in stock
- PackAge: accroding to the need
- Port: Shanghai Port
- ProductionCapacity: 100 Kilogram/Day
- Purity: 98% purity
- Storage: Sealed in dry,Room Temperature
- Transportation: air,sea and courier
- LimitNum: 1 Gram
- Grade: Industrial Grade,Pharma Grade,Electron...
Superiority
Product Name: (S)-3-Hydroxypyrrolidine
Synonyms: (S)-3-PYRROLIDINOL (S)-3-HYDROXYPYRROLIDINE;(S)-(-)-3-PYRROLIDINOL;(S)-3-PYRROLIDINOL;(S)-3-Hydroxypyrrolidine ((S)-3-Pyrrolidinol);(S)-3-HYDROXYPYROLIDINE HYDROCHLORIDE;(S)-(-)-3-Hydroxypyrrolidine, 99%, ee 99+%;(S)-3-Pyrrolidinol,99%e.e.;(S)-3-Pyrrolidinol >=97.0% (sum of enantiomers, GC)
CAS: 100243-39-8
MF: C4H9NO
MW: 87.12
EINECS: 600-044-6
Mol File: 100243-39-8.mol
Details
Melting point 15°C
alpha -6.5 º (c=3.5% in MeOH)
Boiling point 108-110 °C (8 mmHg)
density 1.078 g/mL at 20 °C (lit.)
refractive index n20/D 1.490
Fp >110°C
storage temp. 2-8°C
pka 14.91±0.20(Predicted)
form Liquid After Melting
color Clear light yellow to yellow
Specific Gravity 1.078
optical activity [α]20/D 6.5±1.5°, c = 3.5% in methanol
Water Solubility Fully miscible in water.
Sensitive Air Sensitive & Hygroscopic
BRN 4652606
CAS DataBase Reference 100243-39-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-40
Safety Statements 26-37/39-36-22
WGK Germany 3
F 10-34
HS Code 29339900
MSDS Information
Provider Language
(S)-3-Hydroxypyrrolidine English
ACROS English
SigmaAldrich English
ALFA English
(S)-3-Hydroxypyrrolidine Usage And Synthesis
Chemical Properties clear light yellow to yellow liquid after melting
Purification Methods The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(S)-3-Hydroxypyrrolidine Preparation Products And Raw materials
Preparation Products LOXO-101 (sulfate)