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Home > Products >  S)-3-Hydroxypyrrolidine

S)-3-Hydroxypyrrolidine CAS NO.100243-39-8

  • Min.Order: 1 Gram
  • Payment Terms: T/T,Other
  • Product Details

Keywords

  • S)-3-Hydroxypyrrolidine
  • 100243-39-8
  • 98% purity

Quick Details

  • ProName: S)-3-Hydroxypyrrolidine
  • CasNo: 100243-39-8
  • Molecular Formula: C4H9NO
  • Appearance: powder
  • Application: intermediate
  • DeliveryTime: in stock
  • PackAge: accroding to the need
  • Port: Shanghai Port
  • ProductionCapacity: 100 Kilogram/Day
  • Purity: 98% purity
  • Storage: Sealed in dry,Room Temperature
  • Transportation: air,sea and courier
  • LimitNum: 1 Gram
  • Grade: Industrial Grade,Pharma Grade,Electron...

Superiority

Product Name:    (S)-3-Hydroxypyrrolidine
Synonyms:    (S)-3-PYRROLIDINOL (S)-3-HYDROXYPYRROLIDINE;(S)-(-)-3-PYRROLIDINOL;(S)-3-PYRROLIDINOL;(S)-3-Hydroxypyrrolidine ((S)-3-Pyrrolidinol);(S)-3-HYDROXYPYROLIDINE HYDROCHLORIDE;(S)-(-)-3-Hydroxypyrrolidine, 99%, ee 99+%;(S)-3-Pyrrolidinol,99%e.e.;(S)-3-Pyrrolidinol >=97.0% (sum of enantiomers, GC)
CAS:    100243-39-8
MF:    C4H9NO
MW:    87.12
EINECS:    600-044-6
Mol File:    100243-39-8.mol
 

Details

Melting point     15°C
alpha     -6.5 º (c=3.5% in MeOH)
Boiling point     108-110 °C (8 mmHg)
density     1.078 g/mL at 20 °C (lit.)
refractive index     n20/D 1.490
Fp     >110°C
storage temp.     2-8°C
pka    14.91±0.20(Predicted)
form     Liquid After Melting
color     Clear light yellow to yellow
Specific Gravity    1.078
optical activity    [α]20/D 6.5±1.5°, c = 3.5% in methanol
Water Solubility     Fully miscible in water.
Sensitive     Air Sensitive & Hygroscopic
BRN     4652606
CAS DataBase Reference    100243-39-8(CAS DataBase Reference)
Safety Information
Hazard Codes     Xi,Xn
Risk Statements     36/37/38-40
Safety Statements     26-37/39-36-22
WGK Germany     3
F     10-34
HS Code     29339900
MSDS Information
Provider    Language
(S)-3-Hydroxypyrrolidine    English
ACROS    English
SigmaAldrich    English
ALFA    English
(S)-3-Hydroxypyrrolidine Usage And Synthesis
Chemical Properties    clear light yellow to yellow liquid after melting
Purification Methods    The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(S)-3-Hydroxypyrrolidine Preparation Products And Raw materials
Preparation Products    LOXO-101 (sulfate)
 

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