6-Fluoro-4-nitro-3H-isobenzofuran-1-one CAS NO.1207453-90-4

Product Name:    6-Fluoro-4-nitro-3H-isobenzofuran-1-one
Synonyms:    6-Fluoro-4-nitro-3H-isobenzofuran-1-one;6-fluoro-4-nitroisobenzofuran-1(3H)-one;TALAZ-001;6-FLUOR-4-NITROISOBENZOFURAN-1(3H)-ONE;104156;1(3H)-Isobenzofuranone, 6-fluoro-4-nitro-;6-Fluoro-4-nitro-1(3H)-isobenzofuranone
CAS:    1207453-90-4
MF:    C8H4FNO4
MW:    197.12                 
Mol File:    1207453-90-4.mol        

6-Fluoro-4-nitro-3H-isobenzofuran-1-one Chemical Properties
Boiling point     414.9±45.0 °C(Predicted)
density     1.614±0.06 g/cm3(Predicted)
storage temp.     Sealed in dry,Room Temperature
Safety Information
MSDS Information
6-Fluoro-4-nitro-3H-isobenzofuran-1-one Usage And Synthesis
Description    6-fluoro-4-nitro-3H-isobenzofuran-1-one is a kind of benzofuran derivative. As a kind of isobenzofuranone, it can be used to enhance aroma in perfumery. It also has certain pharmacological effects such as antioxidant activity and antiplatelet activity.
6-Fluoro-4-nitro-1(3H)-isobenzofuranone appeared as a reactant in the synthesis of a Poly(ADP-ribose) Polymerase-1/2 Inhibitor, which is a proposed anticancer agent.
References    Boden, Richard M, and W. L. Schreiber. "Use of 1 (3H)- isobenzofuranone in perfumery." US, US 5665697 A. 1997.
Ma, F., et al. "Antiplatelet activity of 3-butyl-6-bromo-1 (3H)- isobenzofuranone on rat platelet aggregation. " Journal of Thrombosis & Thrombolysis 33.1(2012): 64-73.
Pahari, Pallab, B. Senapati, and D. Mal. "Regiospecific Synthesis of Isopestacin, a Naturally Occurring Isobenzofuranone Antioxidant." Cheminform 45.26(2004): 5109-5112.
6-Fluoro-4-nitro-3H-isobenzofuran-1-one Preparation Products And Raw materials
Preparation Products    BMN 673