2-(Di-tert-butylphosphino)biphenyl CAS NO.224311-51-7

Product Name:    2-(Di-tert-butylphosphino)biphenyl
Synonyms:    (2-biphenyl)di-tert-butylphosphine;(2-BIPHENYLYL)DI-TERT-BUTYLPHOSPHINE;2-(DI-TERT-BUTYLPHOSPHINO)BIPHENYL;2-(DI-T-BUTYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YL-DI-TERT-BUTYL-PHOSPHANE;2-(Di-t-butylphosphino)biphenyl,99%JohnPhos;2-(Di-t-butylphosphine) biphenyl;PHOSPHINE, [1,1''-BIPHENYL]-2-YLBIS(1,1-DIMETHYLETHYL)-
CAS:    224311-51-7
MF:    C20H27P
MW:    298.4
EINECS:    607-074-9
Product Categories:    Achiral Phosphine;Aryl Phosphine;Ligand;organophosphine ligand;Buchwald Ligands Series;Buchwald Ligands&Precatalysts;Benzene derivatives;Phosphines;Phosphine Ligands;Synthetic Organic Chemistry
Mol File:    224311-51-7.mol
Melting point     86-88 °C (lit.)
Boiling point     405.5±24.0 °C(Predicted)
density     1 g/cm3
form     Crystals or Crystalline Powder
color     White
Water Solubility     Insoluble
BRN     8322131
InChIKey    CNXMDTWQWLGCPE-UHFFFAOYSA-N
CAS DataBase Reference    224311-51-7(CAS DataBase Reference)
Safety Information
Hazard Codes     Xn
Risk Statements     36/37/38-22
Safety Statements     36/37/39-26-22
WGK Germany     3
F     10-23
TSCA     No
HazardClass     AIR SENSITIVE
HS Code     29029090
MSDS Information
Provider    Language
ACROS    English
SigmaAldrich    English
ALFA    English
2-(Di-tert-butylphosphino)biphenyl Usage And Synthesis
Reactions    
Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates.
Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates.
Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides.
Effective ligand used in palladium-catalyzed arylation of thiazoles.
Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation.
Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones.

Chemical Properties    white to light yellow crystal powde
Uses    suzuki reaction

Product Name:    2-(Di-tert-butylphosphino)biphenyl
Synonyms:    (2-biphenyl)di-tert-butylphosphine;(2-BIPHENYLYL)DI-TERT-BUTYLPHOSPHINE;2-(DI-TERT-BUTYLPHOSPHINO)BIPHENYL;2-(DI-T-BUTYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YL-DI-TERT-BUTYL-PHOSPHANE;2-(Di-t-butylphosphino)biphenyl,99%JohnPhos;2-(Di-t-butylphosphine) biphenyl;PHOSPHINE, [1,1''-BIPHENYL]-2-YLBIS(1,1-DIMETHYLETHYL)-
CAS:    224311-51-7
MF:    C20H27P
MW:    298.4
EINECS:    607-074-9
Product Categories:    Achiral Phosphine;Aryl Phosphine;Ligand;organophosphine ligand;Buchwald Ligands Series;Buchwald Ligands&Precatalysts;Benzene derivatives;Phosphines;Phosphine Ligands;Synthetic Organic Chemistry
Mol File:    224311-51-7.mol
Melting point     86-88 °C (lit.)
Boiling point     405.5±24.0 °C(Predicted)
density     1 g/cm3
form     Crystals or Crystalline Powder
color     White
Water Solubility     Insoluble
BRN     8322131
InChIKey    CNXMDTWQWLGCPE-UHFFFAOYSA-N
CAS DataBase Reference    224311-51-7(CAS DataBase Reference)
Safety Information
Hazard Codes     Xn
Risk Statements     36/37/38-22
Safety Statements     36/37/39-26-22
WGK Germany     3
F     10-23
TSCA     No
HazardClass     AIR SENSITIVE
HS Code     29029090
MSDS Information
Provider    Language
ACROS    English
SigmaAldrich    English
ALFA    English
2-(Di-tert-butylphosphino)biphenyl Usage And Synthesis
Reactions    
Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates.
Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates.
Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides.
Effective ligand used in palladium-catalyzed arylation of thiazoles.
Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation.
Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones.

Chemical Properties    white to light yellow crystal powde
Uses    suzuki reaction