1-ETHYL-3-(3-DIMETHYLAMINOPROPYL) CARBODIIMIDE 25952-53-8 CAS NO.25952-53-8

Synonyms: (3-dimethylaminopropyl)ethyl-carbodiimidmonohydrochloride;3-propanediamine,n’-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride;edap;edc(reagent);WSCD;WSCI;WATER-SOLUBLE CARBODIIMIDE;1-ETHYL-3-(3-DIMETHYLAMINOPROPYL) CARBODIIMIDE
CAS: 25952-53-8
MF: C8H18ClN3
MW: 191.7
EINECS: 217-579-2
Product Categories: straight chain compounds;Aliphatics;Peptide Coupling Reagents;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Peptide;Amine;peptides;Zero-Length Crosslinker;heteroXlink;EDC
Mol File: 25952-53-8.mol
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Structure
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride Chemical Properties
Melting point  110-115 °C(lit.)
density  0.877 g/mL at 20 °C(lit.)
refractive index  n20/D 1.461
storage temp.  −20°C
Water Solubility  Soluble
Sensitive  Hygroscopic
BRN  5764110
Stability: Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture.
CAS DataBase Reference 25952-53-8(CAS DataBase Reference)
EPA Substance Registry System 1,3-Propanediamine, N'-(ethylcarbonimidoyl)- N,N-dimethyl-, monohydrochloride(25952-53-8)
Safety Information
Hazard Codes  C,Xi
Risk Statements  34-36/37/38-41-37/38-20/21/22
Safety Statements  26-36/37/39-45-37/39-36
RIDADR  UN 2735 8/PG 3
WGK Germany  3
RTECS  FF2200000
F  1-3-10
Hazard Note  Irritant
TSCA  Y
HS Code  29252000

【Synonyms】

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride
1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride
3-(Ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine hydrochloride
Carbodiimide, (3-dimethylaminopropyl)ethyl-, monohydrochloride
【CAS】

25952-53-8
【Formula】

C8H18ClN3
【Molecular Weight】

191.7
【EINECS】

247-361-2
【RTECS】

FF2200000
【RTECS Class】

Other
【Beilstein/Gmelin】

5764110
【EC Class】

irritant
Physical and Chemical Properties Back to Contents
【Appearance】

White solid.
【Solubility in water】

Soluble
【Melting Point】

112 - 113
First Aid Measures Back to Contents
【Ingestion】

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage Back to Contents
【Storage】

Store in a tightly closed container. Store in a dry area. Keep under a nitrogen blanket. Refrigerator (approx 4 C).
【Handling】

Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Do not get on skin or in eyes. Avoid ingestion and inhalation.
Hazards Identification Back to Contents
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
【Inhalation】

Causes respiratory tract irritation.
【Skin】

Causes skin irritation.
【Eyes】

Causes eye irritation.
【EC Risk Phrase】

R 22 36/37/38 42
【EC Safety Phrase】

S 22 26 36/37/39 45
【UN (DOT)】

2811
Exposure Controls/Personal Protection Back to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Fire Fighting Measures Back to Contents
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Accidental Release Measures Back to Contents
【Small spills/leaks】

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment.
Stability and Reactivity Back to Contents
【Disposal Code】

3
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents, strong acids, moist air or water.
【Decomposition】

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Transport Information Back to Contents
【UN Number】

2811
【HS Code】

2925 20 00