Denatonium benzoate 3734-33-6 top supplier CAS NO.3734-33-6

Denatonium benzoate Basic information
The most bitter compound in the world Chemical structure Uses
Product Name: Denatonium benzoate
Synonyms: N,N-DIETHYL-N-[(2,6-DIMETHYLPHENYLCAR-BAMOYL)METHYL]BENZYLAMMONIUM BENZOATE;N-[2-[(2,6-Dimethylphenyl)amino]-2-oxoethyl]-N,N-diethyl-benzenemethanaminium benzoate;REJEXIT (R);,benzoate;Benzenemethanaminium,N-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N,N-diethyl-,benzoate;benzyldiethyl((2,6-xylylcarbamoyl)methyl)-ammoniubenzoate;denatonium;denatoniumbenzoate,anhydrous
CAS: 3734-33-6
MF: C28H34N2O3
MW: 446.58
EINECS: 223-095-2
Product Categories: Miscellaneous Biochemicals;Ammonium Polyhalides, etc. (Quaternary);Quaternary Ammonium Compounds;DIMETANE
Mol File: 3734-33-6.mol
Denatonium benzoate Structure
Denatonium benzoate Chemical Properties
Melting point  164-168 °C(lit.)
solubility  methanol: 50 mg/mL, clear, colorless
Merck  2891
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 3734-33-6(CAS DataBase Reference)
EPA Substance Registry System Benzenemethanaminium, N-[2-[(2,6-dimethylphenyl) amino]-2-oxoethyl]-N,N-diethyl-, benzoate(3734-33-6)
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  26-36-37/39
WGK Germany  2
RTECS  BO6650000
HS Code  29242995

The most bitter compound in the world Denatonium benzoate is now known as the world's most bitter compound. If we set the bitter degree of quinine as datum 1, the degree of bitterness of the product would be 1000. A concentration of 10ppm solution is already too bitter to bear for most people. The vast majority of its applications are related to its bitter flavor. It is an inexpensive and efficient alternative to its counterparts such as strychnine, bitter lignin, quinine, wood song glycosides, saponins grapefruit.
Denatonium benzoate is commonly used as aversive agent to prevent people from eating other toxic but tasteless substance. For example, it has been added into industrial alcohol, ethylene glycol or methanol which has similar taste as ordinary wine, antifreeze, paint, toilet cleaners, animals disperse, liquid soaps and shampoos. Moreover, it has been also added into special nail polish agents, to avoid child’s bad habit of biting fingers, as well as being the repellent for expulsing large beasts. However, the effect of Long-term exposure to this substance on human health is still unclear.
Chemical structure Denatonium benzoate is a kind of quaternary ammonium salt formed by the combination of the quaternary ammonium cation and inert anion such as benzoic acid or saccharin anion. The structure of its cation form is similar to that of a local anesthetic lidocaine with the only difference being an additional benzyl functional group located on the nitrogen atom of the amino.
Uses Flavoring agent.
Chemical Properties white crystals
Usage H1 antihistamine