Astaxanthin 472-61-7 1%，3%，5%，10% CAS NO.472-61-7

Product Name: Astaxanthin
Synonyms: OVEOSTER;(3S,3’S)-3,3’-Dihydroxy-.beta.,.beta.-carotene-4,4’-dione;3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE;3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE;3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE;ASTAXANTHIN;AXN;Astaxanthinenatural
CAS: 472-61-7
MF: C40H52O4
MW: 596.84
EINECS: 207-451-4
Product Categories: Carotenoids;Intermediates & Fine Chemicals;Pharmaceuticals;Plant extracts
Mol File: 472-61-7.mol
Astaxanthin Structure
Astaxanthin Chemical Properties
Melting point  215-216 °C
storage temp.  −20°C
Safety Information
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  29339990
Hazardous Substances Data 472-61-7(Hazardous Substances Data)

Astaxanthin Usage And Synthesis
Product features Shrimp flavin is found in river crayfish shell, oysters and salmon, which is a sort of red carotenoid, It can be combined with the protein in vivo and show green, blue. There are antioxidant, anti-aging, anti-tumor, prevention of cardiovascular and cerebrovascular disease.
Astaxanthin is a kind of lutein, the most widely distributed in the animal kingdom. It is pink, and has unique coloring function, also can promote antibody production, enhancing animal immunity. On the aspects of the antioxidant and scavenging free radicals, the ability is stronger than β-carotene( (10 times). It is soluble in water and lipophilic, soluble in carbon disulfide, acetone, benzene and chloroform and other organic solvents. Astaxanthin is a kind of very potential carotenoid additives, and has a broad prospect in food, feed, cosmetics, pharmaceuticals and other fields. Foods which are rich in the astaxanthin include marine plants, Pluvialis microalgae, Phaffia rhodozyma, wild salmon, shrimp, salmon, rainbow trout and other seafood. Astaxanthin can bring many benefits to health, but not everyone can get enough, this is where the problem.
Natural astaxanthin Natural astaxanthin also known as astacin, is a kind of precious health ingredients, is used for development to enhance immunity, anti-oxidation, anti-inflammatory, eyes and brain health, regulating blood lipids and other natural and healthy products. At present, the main used as a raw material for human health food and medicine; aquaculture (currently the main salmon, trout and salmon), poultry feed additive and additives of cosmetics.
It can significantly improve the body's immunity, because of its non-specific combination with skeletal muscle, can effectively remove the free radicals which are generated by the movement of the muscle cells, strengthen aerobic metabolism, so it has a significant anti fatigue effect.
It is only the carotenoids through blood brain barrier, with true anti-aging effect and effective antioxidant is the basis of all beauty activities. Owing to its powerful antioxidant, It can effectively wrinkle anti-aging, sunscreen whitening and except for chloasma caused by age. In the prevention and treatment for age related macular degeneration and improvement of retinal function, it has good effects. All of the above can clearly be confirmed in the United States.
The stability and antioxidant activity of synthetic astaxanthin also are lower than natural astaxanthin. Because of the hydroxyl (- OH) at ends of the molecule, astaxanthin can be esterification, resulting in not the same of its stability. More than 90% of natural astaxanthin is exist in ester form, and therefore more stable. Synthesic astaxanthin is the free state, therefore, the stability is not the same, must be embedded in order to stabilize. Because Left lateral structure of synthesic astaxanthin was only about 1/4, so it is only natural antioxidant of 1/4.
Production process A method of production of chitin, astaxanthin, protein, calcium powder and biological fertilizer from shrimp shell, its production process is as follows:
1. The shrimp shell is cleaned and mechanical crushing to 5 -10 mesh t.
2. The weight ratio of the shrimp shell powder and the shrimp shell was 1: 1-2, and the protease was added to the solution. According to different varieties of shrimp shell, the temperature of the enzyme solution was 30-70℃, pH value was 4-8, the time was 2-6 hours, and protease was 0.4%-1% of the shrimp shell in weight .
3. After the end of the enzyme solution, the temperature is up to 70-100℃ and then Enzyme bacteria is cool.
4. After that, adding organic solvent extraction, the weight ratio of organic solvent and shrimp shell was 1: 1-2, stirred closed fully 6-12 hours then cooling.
5. After full reaction, separate the liquid of shrimp and shrimp.
6. Shrimp liquid is divided into liquid and organic liquid.
Uses Natural astaxanthin also known as astacin, is a kind of precious health ingredients, is used for development to enhance immunity, anti-oxidation, anti-inflammatory, eyes and brain health, regulating blood lipids and other natural and healthy products. At present, the main used as a raw material for human health food and medicine; aquaculture (currently the main salmon, trout and salmon), poultry feed additive and additives of cosmetics. It can significantly improve the body's immunity, because of its non-specific combination with skeletal muscle, can effectively remove the free radicals which are generated by the movement of the muscle cells, strengthen aerobic metabolism, so it has a significant anti fatigue effect.
Health Benefits of Astaxanthin (1) Astaxanthin is a powerful antioxidant. The free radical scavenging activity of astaxanthin protects lipids from peroxidation and reduces oxidative damage of LDL-cholesterol (thereby reducing arterial plaque formation), cells, cell membranes, mitochondrial membranes. Astaxanthin increases strength and endurance.
(2) Astaxanthin seems to improve the immune system by increasing the number of antibody producing cells. Astaxanthin enhances antibody production by exerting actions on T-cells and T-helper cells. Astaxanthin is used to treat neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease.
(3) Astaxanthin protects the eyes and skin from sun radiation damage by quenching singlet and triplet oxygen. Studies with rats show that astaxanthin reduces retinal injury.
(4) Studies have shown the anti-cancer effects of astaxanthin in rodents. The inhibitory effect of astaxanthin on cancer is stronger han that of beta-carotene.
Side Effects of Astaxanthin You should also know about the side effects of astaxanthin. No toxic side-effects are related with overdose of astaxanthin. However, mild to moderate side effects are noticed with high doses of it. Some side effects include:
Aplastic anemia
Eye damage because of crystal formation
Decreased libido
Reduction in blood pressure,
Enhanced skin pigmentation
Gynecomastia (abnormal enlargement of breasts in men)
Inhibited 5-alpha-reductase
Increased hair growth
Lowered eosinophil counts
Parathyroid intervention
Lowered serum calcium
Inhibited conversion of testosterone to dihydrotestosterone
Dosage Research has shown that the optimal dosage of astaxanthin is 4 mg per day - which relates to 200 mg of a 2% extract.
It is of prime importance that when evaluating any Astaxanthin supplement that you ensure that you ingest 4 mg PER DAY - which would require 200 mg of a 2% extract - as used in our Anti-Aging Supplement.
Toxicity and symptoms of high intake Astaxanthin
Astaxanthin is practically non-toxic in acute animal studies at doses up to 18 grams. When tested for genotoxicity, there was no evidence for mutagenicity in Ames/Salmonella assays nor did it induce micronuclei when tested in vivo up to 2000 mg/kg in mice. There was no maternal, embryo-toxic or teratogenic effects in a teratology study in rabbits given up to 400 mg/kg over most of the gestational period.
No adverse effects were noted in a one-generation reproduction study at doses up to 400 mg/kg in rats. In multiple subchronic feeding studies in rats, astaxanthin did not produce any adverse toxicological effects.
Chemical Properties Drak-Purple Solid
Usage Carotenoid pigment found mostly in animal organisms, but also occuring in plants; thought to be the precursor of astacin. Animal studies indicate that it reduces blood glucose and ameliorates several parameters of the diabetic metabolic syndrome. It improves blood flow and vascular tone in models of hypertension.