Daidzein 486-66-8 Large in promotion CAS NO.486-66-8

Synonyms: 4’,7-dihydroxy-isoflavon;7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone;7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-on;daidzeol;k251b;AKOS NCG1-0027;7-HYDROXY-3-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE;7-HYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
CAS: 486-66-8
MF: C15H10O4
MW: 254.24
EINECS: 207-635-4
Product Categories: Iso-Flavones;pharmacetical;Biochemistry;Flavonoids;The group of Daidzin;Inhibitors;Tyrosine Kinase Inhibitors;Intracellular receptor;Indazoles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;inhibitor;natural product;API
Mol File: 486-66-8.mol
Daidzein Structure
Daidzein Chemical Properties
Melting point  315-323°C (dec.)
storage temp.  2-8°C
solubility  DMSO: 10 mg/mL
form  Powder
color  White to off-white
Water Solubility  insoluble
Merck  2801
CAS DataBase Reference 486-66-8(CAS DataBase Reference)
EPA Substance Registry System 4H-1-Benzopyran- 4-one, 7-hydroxy-3-(4-hydroxyphenyl)- (486-66-8)
Safety Information
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  24-26-37/39
WGK Germany  3
RTECS  DJ3100040
HazardClass  IRRITANT

Daidzein Chemical Properties

mp  315-323°C (dec.)
storage temp.  2-8°C

solubility  DMSO: 10 mg/mL

Water Solubility  insoluble
Merck  2801
CAS DataBase Reference 486-66-8(CAS DataBase Reference)
EPA Substance Registry System 4H-1-Benzopyran- 4-one, 7-hydroxy-3-(4-hydroxyphenyl)- (486-66-8)

Safety Information

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  24-26-37/39
WGK Germany  3

RTECS  DJ3100040

HazardClass  IRRITANT

Daidzein Usage And Synthesis

Chemical Properties Off-White Crystalline Solid
Usage Inactive analog of Genistein (Cat. #G350000). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity1. Daidzein has also been shown to inhibit the action of GABA on recombinant GABAA receptors2. uv max:250 nm (log e 4.44)
Usage Daidzein belongs to the group of isoflavones. Daidzein and other isoflavone compounds, such as genistein, are present in a number of plants and herbs. Soy isoflavones are a group of compounds found in and isolated from the soybean. Besides functioning as
Usage phytoestrogen
Biological Activity Analog of the phytoestrogen genistein (5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one ). Blocks G 1 phase cell cycle progression and is an agonist at estrogen receptors.

Daidzein Preparation Products And Raw materials

Raw materials Etanol-->Hydrochloric acid-->Diethyl ether