China (Mainland)
Assessedsupplier
Adiphenine hydrochloride CAS NO.50-42-0
- Min.Order: 1 Gram
- Payment Terms: T/T
- Available Specifications:
- Product Details
Keywords
- Aceticacid, diphenyl-, 2-(diethylamino)ethyl ester hydrochloride (8CI)
- Benzeneaceticacid, a-phenyl-, 2-(diethylamino)ethylester, hydrochloride (9CI)
- 2-Diethylaminoethyl diphenylacetate hydrochloride
Quick Details
- ProName: Adiphenine hydrochloride
- CasNo: 50-42-0
- Molecular Formula: C20H26ClNO2
- Appearance: white solid
- Application: 2-(Diethylamino)ethyla-phenylbenzeneac...
- DeliveryTime: in stock
- PackAge: according to the customer
- Port: shanghai
- ProductionCapacity: 1 Metric Ton/
- Purity: 99%
- Storage: Room Temperature
- Transportation: by sea air and courier
- LimitNum: 1 Gram
- Related Substances: 1
- Residue on Ignition: 1
- Heavy Metal: 1
- Valid Period: 1
- 1: 1
- 1: 1
Superiority
InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.
Details
InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.InvitrostudiesAdiphenine(10nM-1mM;3min)blocksthefunctionofα1*-nAChRinadose-dependentmannerinTE671/RDcells,withanIC50of1.9µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα3α4*-nAChRinadose-dependentmannerinSH-SY5Ycells,withanIC50of1.8µM.Adiphenine(10nM-1mM;3min)blocksthefunctionofα4β2-andα4β4-nAChRinChemicalbookadose-dependentmannerinSH-EP1cells,withIC50sof3.7and6.3µM,respectively.Adiphenine(50-200µM;30-60s)decreasesthefrequencyofACh-inducedsingle-channelcurrentsinHEK293cells.InvivostudiesAdiphenine(i.p.)preventsthehindlegtonic-extensorcomponentofmaximalelectroshockseizures(MES),withanED50of62mg/kginmice.