3-Aminophthalhydrazide 521-31-3 purity 99% CAS NO.521-31-3

Product Name: 3-Aminophthalhydrazide
Synonyms: RARECHEM AH BS 0053;AURORA KA-3798;LABOTEST-BB LT00645356;LUMINOL;3-AMINOPHTHALHYDRAZINE;3-AMINOPHTHALIC HYDRAZIDE;3-AMINOPHTHALOYLHYDRAZINE;3-AMINOPHTHALHYDRAZIDE
CAS: 521-31-3
MF: C8H7N3O2
MW: 177.16
EINECS: 208-309-4
Product Categories: Piperazine derivates;Analytical Chemistry;Chemiluminescence;Luminols (Chemiluminescence);Pharmaceutical intermediates;#
Mol File: 521-31-3.mol
3-Aminophthalhydrazide Structure
3-Aminophthalhydrazide Chemical Properties
Melting point  >300 °C(lit.)
storage temp.  0-6°C
Water Solubility  <0.1 g/100 mL at 19 ºC
Merck  14,5600
BRN  383929
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents. Emits light on reaction with oxidizers.
CAS DataBase Reference 521-31-3(CAS DataBase Reference)
NIST Chemistry Reference 3-Aminophthalhydrazide(521-31-3)
EPA Substance Registry System 1,4-Phthalazinedione, 5-amino-2,3-dihydro-(521-31-3)
Safety Information
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22-20/21/22
Safety Statements  26-36/37-37/39-36
WGK Germany  3
RTECS  TH8890060
F  10-23
TSCA  Yes
HS Code  29339990

Uses 1.    It can be used as chemical analysis reagents, indicators.
2.    It can be used for chemiluminescence analysis such as measurement of metal cations, blood and glucocorticoids
Production method It is obtained through the cyclization and reduction of 3-nitrophthalic acid. Add the 3-nitrophthalic acid into 8% aqueous hydrazine solution and melt the solid by heating. Add the ethylene glycol and evaporate the excess amount of water of the solution in the evaporator; heat at 215-220 °C for 2 min and close the heterocyclic ring with cooling generating yellow nitro compounds. After cooling, add 10% sodium hydroxide solution, stir and add sodium dithionite, heat to boiling and maintain the temperature for 5min, then add acetic acid with cooling obtaining bright yellow product. After standing overnight, the product was filtered.
Hazards & Safety Information Category Toxic substances
Toxic grading poisoning
Acute toxicity Oral – rat; LD50: > 500 mg/kg
Flammability and Hazardous properties it is combustible with combustion producing toxic nitrogen oxide fumes
Storage and transportation characteristics warehouse: ventilated, low temperature and dry
Fire extinguishing agent dry powder, foam, sand, carbon dioxide, mist water
Chemical Properties yellow crystals or beige powder
Uses Luminol is a chemiluminescent probe that has been used to detect myeloperoxidase-mediated oxidative events in granulocytes and for chemiluminescence analysis of metal cations and blood.
General Description Yellow crystals or light beige powder.
Air & Water Reactions Insoluble in water.
Reactivity Profile Oxidation of 3-Aminophthalhydrazide is accompanied by a striking emission of light. . .
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Aminophthalhydrazide emits toxic fumes.
Fire Hazard Flash point data for 3-Aminophthalhydrazide are not available, but 3-Aminophthalhydrazide is probably combustible.