Metoclopramide hydrochloride CAS NO.54143-57-6

Product Name:    Metoclopramide hydrochloride
Synonyms:    Annavar;Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride, monohydrate;Metoclopramide monohydrochloride monohydrate;Metoclopramide Hydrochloride (500 mg);METOCLOPRAMIDE HYDROCHLORIDE, MONOHYDRATE;MetoclopraMide Hydrochloride, USP;MetoclopraMide HCI;4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride monohydrate
CAS:    54143-57-6
MF:    C14H22ClN3O2.ClH
MW:    336.26
EINECS:    641-713-2
Product Categories:    API;Steroid and Hormone
Mol File:    54143-57-6.mol

Melting point     182.5-184°
storage temp.     Inert atmosphere,2-8°C
form     neat
Water Solubility     It is very soluble in water, easily soluble in ethyl alcohol, slightly soluble in dichloromethane.
Sensitive     Light Sensitive
InChIKey    RVFUNJWWXKCWNS-UHFFFAOYSA-N
CAS DataBase Reference    54143-57-6(CAS DataBase Reference)
Safety Information
WGK Germany     3
HS Code     2924296000

Originator    Primperan,Delagrange,France,1964
Uses    Dopamine receptor antagonist; antiemetic.
Indications    Metoclopramide (Reglan) stimulates upper GI tract motility and has both central and peripheral actions. Centrally, it is a dopamine antagonist, an action that is important both for its often desirable antiemetic effect and other less desirable effects. Peripherally, it stimulates the release of intrinsic postganglionic stores of acetylcholine and sensitizes the gastric smooth muscle to muscarinic stimulation. The ability of metoclopramide to antagonize the inhibitory neurotransmitter effect of dopamine on the GI tract results in increased gastric contraction and enhanced gastric emptying and small bowel transit.