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Cefmetazole sodium CAS NO.56796-39-5
- Min.Order: 1 Gram
- Payment Terms: T/T
- Available Specifications:
- Product Details
Keywords
- Cefmetazole sodium
- 56796-39-5
- 99%
Quick Details
- ProName: Cefmetazole sodium
- CasNo: 56796-39-5
- Molecular Formula: C15H16N7NaO5S3
- Appearance: white powder
- Application: INTERMEDITD
- DeliveryTime: In stock
- PackAge: According to your needs
- Port: Shang Hai
- ProductionCapacity: 100 Metric Ton/Year
- Purity: 99%
- Storage: Inert atmosphere,2-8°C
- Transportation: Courier Air Sea
- LimitNum: 1 Gram
Superiority
| Cefmetazole sodium Basic information |
| Product Name: | Cefmetazole sodium |
| Synonyms: | Cefmetazone;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-;Cefmetazole-Na;CS-1170 sodium salt;Metafar;Sodium cefmetazole;(6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt |
| CAS: | 56796-39-5 |
| MF: | C15H18N7NaO5S3 |
| MW: | 495.52 |
| EINECS: | 627-393-7 |
| Product Categories: | Sulfur & Selenium Compounds;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity |
| Mol File: | 56796-39-5.mol |
Details
Cefmetazole sodium Chemical Properties
Melting point >130°C (dec.)
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble50mg/mL
form powder
color White to Off-White
Water Solubility Soluble in water
Sensitive Hygroscopic
Merck 14,1926
Stability: Hygroscopic
InChIKey BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference 56796-39-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-42/43
Safety Statements 26-36
WGK Germany 2
RTECS XI0372200
HS Code 2941.90.3000
Toxicity LD50 i.v. in rats: >5000 mg/kg (Masuda)
MSDS Information
Cefmetazole sodium Usage And Synthesis
Chemical Properties White Solid
Uses Semi-synthetic antibiotic derived from Cephamycin. Antibacterial
Uses Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.
Definition ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.
Brand name Zefazone (Pharmacia & Upjohn）.
Clinical Use Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.