D-BIOTIN/ VITAMIN H CAS NO.58-85-5

D-Biotin Basic information
Description Physicochemical property Physiological function Biotin and fat metabolism Biotin deficiency Food source Toxicity Side effect Distinguishing test Content analysis Applications References
Product Name:    D-Biotin
Synonyms:    RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;D-(+)-Biotin,98+%;D-BIOTIN, 1%, 2% (VITAMIN H);ETHYLPHENYLETHANOL;(+)-Biotin , Vitamin B7, Coenzyme R;1H-Thieno3,4-dimidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS,4S,6aR)-;BIOTIN,POWDER,FCC
CAS:    58-85-5
MF:    C10H16N2O3S
MW:    244.31
EINECS:    200-399-3
Product Categories:    Biotinylation Reagents;RONIACOL;Vitamin series;Inhibitor;Isolabel;biotinyl;cyclic compounds;PHARMACEUTICALS;Miscellaneous Natural Products;Other Reagents;Biochemistry;Vitamins;API;Inhibitors;Nutritional Supplements;Vitamins and derivatives;Biotin Derivatives;Intermediates & Fine Chemicals;Vitamin Ingredients;bc0001;58-85-5
Mol File:    58-85-5.mol

D-Biotin Chemical Properties
Melting point     231-233 °C(lit.)
alpha     89 º (c=1, 0.1N NaOH)
Boiling point     573.6±35.0 °C(Predicted)
density     1.2693 (rough estimate)
refractive index     90.5 ° (C=2, 0.1mol/L NaOH)
storage temp.     -20°C
solubility     H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
form     powder
pka    4.74±0.10(Predicted)
color     White crystalline powder or fine long needles
PH    4.5 (0.1g/l, H2O)
optical activity    [α]20/D +91±2°, c = 1% in 0.1 M NaOH
Water Solubility     Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.
Sensitive     Light Sensitive
Merck     14,1231
BRN     86838
Stability:    Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, formaldehyde, chloramine-T, nitrous acid.
InChIKey    YBJHBAHKTGYVGT-ZKWXMUAHSA-N
LogP    0.861 (est)
CAS DataBase Reference    58-85-5(CAS DataBase Reference)
NIST Chemistry Reference    Biotin(58-85-5)
EPA Substance Registry System    Biotin (58-85-5)
Safety Information
Hazard Codes     Xn
Risk Statements     20/21/22-36/37/38
Safety Statements     24/25-36-26
WGK Germany     1
RTECS     XJ9088200
F     8
TSCA     Yes
HS Code     29362930
Hazardous Substances Data    58-85-5(Hazardous Substances Data)
Toxicity    LD50 orally in Rabbit: > 2000 mg/kg