(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL CAS NO.588-36-3

Product Name:    (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
Synonyms:    4-AMINO-2-(METHYLTHIO)-5-PYRIMIDINEMETHANOL;4-AMINO-5-HYDROXYMETHYL-2-(METHYLTHIO)PYRIMIDINE;Methioprim;(4-azanyl-2-methylsulfanyl-pyrimidin-5-yl)methanol;(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL;(4-AMINO-2-METHYLSULFANYL-PYRIMIDIN-5-YL)-METHANOL;4-AMINO-2-METHYLMERCAPTO-PYRIMIDINE-4-CARBINOL;(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)ME...
CAS:    588-36-3
MF:    C6H9N3OS
MW:    171.22
EINECS:    
Mol File:    588-36-3.mol

Melting point     126-127°
Boiling point     408.6±30.0 °C(Predicted)
density     1.38±0.1 g/cm3(Predicted)
storage temp.     Keep in dark place,Inert atmosphere,2-8°C
pka    13.08±0.10(Predicted)
Safety Information
HS Code     29335990
MSDS Information
(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Usage And Synthesis
Chemical Properties    (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is white cryst powder
Uses    Tumor antagonist in mice.
Uses    (4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is an intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.
(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Preparation Products And Raw materials
Raw materials    Ethanol-->Tetrahydrofuran-->Sodium-->Toluene-->Acetic anhydride-->Lithium Aluminum Hydride-->Isopropyl alcohol-->Triethyl orthoformate-->Ethyl cyanoacetate-->Thiourea-->N,N-Dimethylformamide dimethyl acetal