Ketoconazole CAS NO.65277-42-1

Ketoconazole Basic information

Product Name:    Ketoconazole
Synonyms:    ,3-dioxolan-4-yl)methoxy)phenyl)-,cis-;fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral
CAS:    65277-42-1
MF:    C26H28Cl2N4O4
MW:    531.43
EINECS:    265-667-4
Product Categories:   
Mol File:    65277-42-1.mol
 

Ketoconazole Chemical Properties
Melting point     148-152 °C
Boiling point     753.4±60.0 °C(Predicted)
density     1.4046 (rough estimate)
refractive index     -10.5 ° (C=0.4, CHCl3)
Fp     9℃
storage temp.     2-8°C
solubility     methanol: soluble50mg/mL
pka    pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
form     Off-white solid
color     white to light yellow
optical activity    [α]20/D -1 to 1°, c = 4 in methanol
Water Solubility     Soluble in DMSO, ethanol, chloroform, water, and methanol.
Merck     14,5302
InChIKey    XMAYWYJOQHXEEK-OZXSUGGESA-N
CAS DataBase Reference    65277-42-1(CAS DataBase Reference)

Safety Information
Hazard Codes     T,N,F
Risk Statements     25-36/37/38-23/24/25-50/53-48/22-60-39/23/24/25-11
Safety Statements     36-45-36/37/39-26-61-60-53-36/37-16-7
RIDADR     UN 2811 6.1/PG 3
WGK Germany     3
RTECS     TK7912300
HazardClass     6.1(b)
PackingGroup     III
HS Code     29349990
Hazardous Substances Data    65277-42-1(Hazardous Substances Data)
Toxicity    LD50 in mice, rats, guinea pigs, dogs (mg/kg): 44, 86, 28, 49 i.v.; 702, 227, 202, 780 orally (Heel)