Methanesulfonic acid 75-75-2 top seller in China CAS NO.75-75-2

Product Name: Methanesulfonic acid
Synonyms: SULFOMETHANE;MSA;acidemethanesulfonique;Kyselina methansulfonova;kyselinamethansulfonova;Methylsulphonicacid;Sulphonethane;METHANESULFONIC ACID
CAS: 75-75-2
MF: CH4O3S
MW: 96.11
EINECS: 200-898-6
Product Categories: HPLC;HPLC Buffer;HPLC Buffers;HPLC Buffers - SolutionChromatography/CE Reagents;Solution;Chromatography/CE Reagents;Eluent concentrates for ICAlphabetic;Ion Chromatography;M;META - METH;Chemical Synthesis;Organic Acids;Synthetic Reagents;Organic AcidsAnalytical Reagents;Products for Amino Acid Hydrolysis;Amino Acid Analysis;Essential Chemicals;Reagent Plus;Routine Reagents;Others;Supported Reagents;Supported Synthesis;Agrochemical Intermediates, Pharmaceutical Intermediates
Mol File: 75-75-2.mol
Methanesulfonic acid Structure
Methanesulfonic acid Chemical Properties
Melting point  19 °C
Boiling point  167 °C10 mm Hg(lit.)
density  1.481 g/mL at 25 °C(lit.)
vapor density  3.3 (vs air)
vapor pressure  1 mm Hg ( 20 °C)
refractive index  n20/D 1.429(lit.)
Fp  >230 °F
storage temp.  2-8°C
color  brown
Sensitive  Light Sensitive & Hygroscopic
Merck  14,5954
BRN  1446024
Stability: Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).
CAS DataBase Reference 75-75-2(CAS DataBase Reference)
NIST Chemistry Reference CH3SO3H(75-75-2)
EPA Substance Registry System Methanesulfonic acid(75-75-2)
Safety Information
Hazard Codes  C
Risk Statements  34-22-21/22-35
Safety Statements  26-36-45-1/2-36/37/39
RIDADR  UN 3265 8/PG 2
WGK Germany  1
RTECS  PB1140000
HazardClass  8
PackingGroup  III
HS Code  29041000
Hazardous Substances Data 75-75-2(Hazardous Substances Data)

Methanesulfonate electroplating solution Methanesulfonic acid is a caustic chemical, briefly referred to as MSA. It has broad application prospect in the field of electroplating and has proved to be an excellent alternative of fluoride boric acid or phenolsulfonic acid.
Methanesulfonate electroplating solution has been applied to tin and tin-lead alloy plating, the product features are as follows:
1. The bright pure tin electroplating of the methanesulfonic acid type with the coating crystal being meticulous, even and exhibiting bright silver-white. It has excellent weldability, being suitable in the electronics profession.
2. The plating solution has a high plating rate, a wide range of current density, faster deposition rate, and excellent deep plating capacity.
3. After the standard aging test or long-term storage, it can still maintain good welding performance.
4. It contains no fluorine boric acid with easy wastewater treatment, low corrosion, being environmentally friendly.
Chemical properties It appears as colorless or slightly brown oily liquid, appearing as solid at low temperatures. It has a melting temperature of 20 °C, the boiling point of 167 °C (13.33 kPa), 122 °C (0.133 kPa),  the relative density of 1.4812 (18 ℃) and refractive index 1.4317 (16 ℃). It is soluble in water, alcohol and ether, insoluble in alkanes, benzene and toluene. It will not subject to decomposition in boiling water and hot alkaline solution. It also has strong corrosion effect against the metal iron, copper and lead.
Uses Methanesulfonic acid is a raw material for medicine and pesticide. It can also be used as dehydrating agent, curing accelerator for coating, treating agent for fiber, solvent, catalysis, and esterification as well as polymerization reaction.
It can be used as solvent, alkylation, catalyst of esterification and polymerization, also used in medicine and electroplating industry. It can also be applied to oxidation.
Production method It can be obtained through the nitrate oxidation of thiocyanate methyl. Nitric acid and negative water are heated carefully to 80-88 °C with fractional addition of methyl thiocyanate and the temperature being automatically rose to about 105 ℃. After the reaction becomes mild, the reaction was heated to 120 ° C and reacted for 5 hours to obtain a crude product. The crude product was diluted with exchanged water and adjusted to pH 8-9 by addition of 25% barium hydroxide solution and filtered. The filtrate is condensed to until crystalline precipitation. The crystal is washed by methanol to remove the nitrate to obtain the barium methanesulfonate. It is then added to the exchanged water to boiling, add sulfuric acid for decomposition while it is hot, filter and the filtrate was concentrated under vacuum to no water to obtain the finished product.
Another method is that the methyl isothiourea sulfate is successively subject to chlorination, oxidation and hydrolysis to derive the finished product. Methyl isothiourea sulfate was added to the water; and the chlorine is sent into at 20-25 ° C to until phenomenon such as solution color is turned into yellow; oil layer emerges in the bottom of the bottle; the temperature drop and large number of residual chlorine is discharged from the exhaust pipe; this indicates the end point of the reaction. The reaction solution was extracted with chloroform. After drying, the extract was distilled at 60-62 ° C under normal pressure to remove the chloroform, and then further subject to distillation under reduced pressure. Collect the 60-65 °C (2.67 kPa) fraction was to obtain the methanesulfonyl chloride. Add the base drop wise under stirring to 80 ℃ hot water and maintain the heat hydrolysis for about 2h, to until the reaction liquid droplets completely disappear. The reaction solution was concentrated under reduced pressure to a syrupy form, diluted with water, and concentrated under reduced pressure to until no more water was distilled off to obtain methanesulfonic acid.
Category Corrosive items
Toxicity classification highly toxic
Acute toxicity Oral - rat LDL0: 200 mg / kg
Flammability and Hazardous properties Flammable with thermal decomposition of toxic formaldehyde and sulfur dioxide smoke
Storage and transportation characteristics Treasury: ventilated, low-temperature, dry; store it separately from oxidants and alkali.
Fire extinguishing agent sand, foam, mist water
Chemical Properties colourless or light yellow liquid
Methanesulfonic acid Preparation Products And Raw materials
Preparation Products Methanesulfonyl chloride-->(S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE-->(S)-1,1'-SPIROBIINDANE-7,7'-DIOL-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE-->Sodium dodecylbenzenesulphonate-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-PHENOXY-->10-(2-Benzothiazolyl)-2,3,6,7-tetrahydro-1,1,7,7-tetramethyl-1H,5H,11H-(1)benzopyropyrano(6,7-8-I,j)quinolizin-11-one-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE-->1,1'-SPIROBIINDANE-7,7'-DIOL-->ETHYL 4-FORMYL-2,5-DIMETHYL-1-(2-THIENYLMETHYL)-1H-PYRROLE-3-CARBOXYLATE-->Fluconazole-->Pazufloxacin-->Pergolide-->Dicofol-->5-Methoxy-3-indazolecarboxylic acid-->Coumarin 314T-->Ethofenprox -->9-Formyl-8-hydroxy-1,1,7,7-tetramethyljulolidine-->5-Methoxyisatin-->3-Aminobenzamide-->LIMAPROST-->Methanesulfonic anhydride -->Pefloxacin-->Gabexate mesylate-->TROVAFLOXACIN-->SAPERCONAZOLE-->Sodium trifluoromethanesulfonate-->Phentolamine mesilate
Raw materials Methanesulfonyl chloride-->2-Methyl-2-thiopseudourea sulfate-->Barium hydroxide -->DMDS-->ANION STANDARD - NITRATE-->Methyl thiocyanate