Cefixime CAS NO.79350-37-1

Product Name:    Cefixime
Synonyms:    YTTERBIUM(III) IONOPHORE I;)(carboxymethoxy)imino)acetylamino)-3-ethenyl-8-oxo-,(6r-(6-alpha,7-beta(z)));cl284635;fk027;fr17027;8-[[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-4-ethenyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid;(6R,7R)-7-[2-(2-AMINO-4-THIAZOLYL)GLOXYLAMIDO]-8-OXO-3-VINYL-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID, 72-(Z)-[O-(CARBOXYMETHYL)OXIME]TRIHYDRATE;CEFIXME TRIHYDRATE
CAS:    79350-37-1
MF:    C16H15N5O7S2
MW:    453.45
EINECS:    616-684-4
Product Categories:    Pharmaceutical intermediates;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Heterocycles;cephalosporins
Mol File:    79350-37-1.mol

Melting point     218-225°C
density     1.85±0.1 g/cm3(Predicted)
storage temp.     Keep in dark place,Inert atmosphere,2-8°C
solubility     Slightly soluble in water, soluble in methanol, sparingly soluble in anhydrous ethanol, practically insoluble in ethyl acetate.
pka    pKa 2.10 (Uncertain)
Water Solubility     55.11 mg/L
CAS DataBase Reference    79350-37-1(CAS DataBase Reference)
Safety Information
Hazard Codes     Xn
Risk Statements     42/43
Safety Statements     22-36/37-45
WGK Germany     3
F     10-23
HS Code     38210000
Toxicity    LD50 oral in rat: > 10gm/kg

Brand Name(s) in US    Suprax
Cephalosporin antibiotics    Cefixime is a third-generation oral cephalosporin antibiotic, also known as Oroken, Suprax, Cefspan, in clinic used for the treatment of bacterial infectious diseases caused by Streptococcus (except Enterococci), Pneumonia chain, Neisseria gonorrhoeae, Escherichia coli, Branhamella catarrhalis, Serratia bacteria, Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Haemophilus influenzae, Klebsiella, Serratia, Proteus and Haemophilus Influenzae, etc. the indications are as follow:
1. respiratory infections, such as pneumonia, tonsillitis, pharyngitis, bronchiectasis (infection), secondary infection of chronic respiratory infectious diseases ,acute and chronic bronchitis, etc.
2. urinary and reproductive tract infections, such as gonococcal urethritis, cervicitis, pyelonephritis, cystitis, gonorrhea , etc.
3. intra-abdominal infections (including cholecystitis, cholangitis, peritonitis).
4. scarlet fever, otitis media, sinusitis and so on.