4-NITROPHENYL ACETATE CAS NO.830-03-5

Product Name:    4-NITROPHENYL ACETATE
Synonyms:    4-Nitrophenylacetat;4-Nitropheyl acetate;Acetic acid, p-nitrophenyl ester;aceticacid,p-nitrophenylester;Essigsαure-4-nitrophenylester;Phenol, p-nitro-, acetate;4-NITROPHENYL ACETATE 98+%;4-Acetoxy-1-nitrobenzene
CAS:    830-03-5
MF:    C8H7NO4
MW:    181.15
EINECS:    212-593-5                        
Mol File:    830-03-5.mol                  
 

4-NITROPHENYL ACETATE Chemical Properties
Melting point     75-77 °C (lit.)
Boiling point     314.24°C (rough estimate)
density     1.4283 (rough estimate)
refractive index     1.5468 (estimate)
storage temp.     -20°C
solubility     0.53g/l
form     Powder
color     Green
Water Solubility     Insoluble in water.
BRN     515874
Stability:    Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference    830-03-5(CAS DataBase Reference)
EPA Substance Registry System    Acetic acid, 4-nitrophenyl ester (830-03-5)
Safety Information
Hazard Codes     F,C
Risk Statements     11-34
Safety Statements     24/25-45-36/37/39-26-16
WGK Germany     3
RTECS     AJ1150000
TSCA     Yes
HS Code     29153900
Toxicity    LD50 ivn-mus: 180 mg/kg CSLNX* NX#00217
MSDS Information
Provider    Language
ACROS    English
SigmaAldrich    English
ALFA    English
4-NITROPHENYL ACETATE Usage And Synthesis
Chemical Properties    off-white or beige powder
Uses    4-Nitrophenyl Acetate have been used as a substrate to study for the enzymatic activity of Carbonic Anhydrase III isolated from bovine skeletal muscle.
Definition    ChEBI: An acetate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of acetic acid.
Synthesis Reference(s)    Synthesis, p. 991, 1981 DOI: 10.1055/s-1981-29674
Safety Profile    Poison by intravenous route. Whenheated to decomposition it emits toxic fumes of NOx.
Purification Methods    Recrystallise the ester from absolute EtOH [Moss et al. J Am Chem Soc 108 5520 1986]. [Beilstein 6 IV 1298.]
4-NITROPHENYL ACETATE Preparation Products And Raw materials
Preparation Products    4-Nitrophenol-->2,3,5,6-Tetrafluorophenol-->acetate-->6-NITROCOUMARIN-->P-NITROPHENYL BUTYRATE-->(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane