N-ACETYL-L-TYROSINE ETHYL ESTER CAS NO.840-97-1

Product Name:    N-ACETYL-L-TYROSINE ETHYL ESTER
Synonyms:    N-ALPHA-ACETYL-L-TYROSINE ETHYL ESTER;N-ACETYL-L-TYR ETHYL ESTER;N-ACETYL-L-TYROSINE ETHYL ESTER;ethyln-alpha-acetyl-tyrosinate;ATEE;ETHYLACETYL-L-TYROSINE;AC-TYR-OET;AC-TYROSINE-OET
CAS:    840-97-1
MF:    C13H17NO4
MW:    251.28
EINECS:    212-663-5
Product Categories:    Amino Acid Ethyl Esters;Amino Acids (C-Protected);Amino Acids;Ac-Amino Acids;Amino Acids (N-Protected);Biochemistry
Mol File:    840-97-1.mol
 

Melting point     78-81 °C
Boiling point     394.43°C (rough estimate)
density     1.1667 (rough estimate)
refractive index     22 ° (C=1, EtOH)
storage temp.     Sealed in dry,2-8°C
pka    9.75±0.15(Predicted)
Water Solubility     3.48g/L(28 ºC)
CAS DataBase Reference    840-97-1(CAS DataBase Reference)
EPA Substance Registry System    L-Tyrosine, N-acetyl-, ethyl ester (840-97-1)
Safety Information
Safety Statements     24/25
WGK Germany     3
F     10-21

Enzyme inhibitor    This ester (FW = 251.28 g/mol; Abbreviation ATEE) is a substrate for chymotrypsin that is frequently used in assays of that enzyme. The reaction can be followed by observing the production of free carboxyl groups or by the decrease in absorbance at 237 nm and pH 7. Supersaturated stock solutions (i.e., 10-20 mM) can be prepared by dissolving ATEE in water at 85°C, followed by rapidly cooling to room temperature. These solutions are typically stable for six to twelve hours. N-Acetyl-L-tyrosine ethyl ester inhibits protein-disulfide reductase, glutathione-requiring; thiolsubtilisin; complement component C’.