5-Aminosalicylic acid CAS NO.89-57-6

Product Name:    5-Aminosalicylic acid

MF:    C7H7NO3
MW:    153.14
EINECS:    201-919-1

Mol File:    89-57-6.mol
5-Aminosalicylic acid Structure
5-Aminosalicylic acid Chemical Properties
Melting point     275-280 °C (dec.) (lit.)
Boiling point     276.03°C (rough estimate)
density     1.3585 (rough estimate)
refractive index     1.5500 (estimate)
Fp     279-281°C
storage temp.     2-8°C
solubility     Soluble in dimethyl sulfoxide.
form     tablets
pka    2.74, 5.84(at 25℃)
color     off-white to gray
PH    4.0-4.1 (0.8g/l, H2O, 20℃)
PH Range    Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility     <0.1 g/100 mL at 21 ºC
Decomposition     279-281 ºC
Merck     14,5904
BRN     2090421
Stability:    Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application    Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey    KBOPZPXVLCULAV-UHFFFAOYSA-N
CAS DataBase Reference    89-57-6(CAS DataBase Reference)
NIST Chemistry Reference    Mesalamine(89-57-6)
EPA Substance Registry System    Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
Safety Information
Hazard Codes     Xi
Risk Statements     36/37/38-52/53
Safety Statements     26-36-24/25-61-37/39
WGK Germany     2
RTECS     VO1400000
F     8-10-23
Autoignition Temperature    280 °C
Hazard Note     Irritant
TSCA     Yes
HazardClass     IRRITANT
HS Code     29225000
Hazardous Substances Data    89-57-6(Hazardous Substances Data)
Toxicity    LD50 orally in Rabbit: 2800 mg/kg LD50 dermal Rat > 5000 mg/kg

Product Name:    5-Aminosalicylic acid

MF:    C7H7NO3
MW:    153.14
EINECS:    201-919-1

Mol File:    89-57-6.mol
5-Aminosalicylic acid Structure
5-Aminosalicylic acid Chemical Properties
Melting point     275-280 °C (dec.) (lit.)
Boiling point     276.03°C (rough estimate)
density     1.3585 (rough estimate)
refractive index     1.5500 (estimate)
Fp     279-281°C
storage temp.     2-8°C
solubility     Soluble in dimethyl sulfoxide.
form     tablets
pka    2.74, 5.84(at 25℃)
color     off-white to gray
PH    4.0-4.1 (0.8g/l, H2O, 20℃)
PH Range    Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility     <0.1 g/100 mL at 21 ºC
Decomposition     279-281 ºC
Merck     14,5904
BRN     2090421
Stability:    Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application    Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey    KBOPZPXVLCULAV-UHFFFAOYSA-N
CAS DataBase Reference    89-57-6(CAS DataBase Reference)
NIST Chemistry Reference    Mesalamine(89-57-6)
EPA Substance Registry System    Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
Safety Information
Hazard Codes     Xi
Risk Statements     36/37/38-52/53
Safety Statements     26-36-24/25-61-37/39
WGK Germany     2
RTECS     VO1400000
F     8-10-23
Autoignition Temperature    280 °C
Hazard Note     Irritant
TSCA     Yes
HazardClass     IRRITANT
HS Code     29225000
Hazardous Substances Data    89-57-6(Hazardous Substances Data)
Toxicity    LD50 orally in Rabbit: 2800 mg/kg LD50 dermal Rat > 5000 mg/kg