Ruxolitinib CAS NO.941678-49-5

Ruxolitinib Basic information

Pharmacological effects Biological Activity Indications Dosage Side effects Other clinical research
Product Name:    Ruxolitinib
Synonyms:    (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile;(3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile;INCB018424 (Ruxolitinib);Jakafi;Roxolitinib;β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-(βR)-1H-pyrazole-1-propanenitrile
CAS:    941678-49-5
MF:    C17H18N6
MW:    306.37
EINECS:    1312995-182-4
Product Categories:    JAK;STAT;APIs;Inhibitor;Anti-cancer&immunity;Inhibitors;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Antineoplastic;API
Mol File:    941678-49-5.mol

Ruxolitinib Chemical Properties
density     1.40
storage temp.     -20°
solubility     Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
form     White powder.
pka    11.63±0.50(Predicted)
color     White
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS DataBase Reference    941678-49-5

Safety Information
HS Code     29335990
Hazardous Substances Data    941678-49-5(Hazardous Substances Data)

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